Advanced Face Mask Filters Based on PCL Electrospun Meshes Dopped with Antimicrobial MgO and CuO Nanoparticles.

Autor: Ferreira CAM; Centre for Rapid and Sustainable Product Development (CDRSP), Instituto Politécnico de Leiria, 2030-028 Marinha Grande, Portugal.; Abel Salazar Institute of Biomedical Sciences (ICBAS), University of Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal.; Centro de Estudos de Ciência Animal (CECA), Instituto de Ciências, Tecnologias e Agroambiente (ICETA) da Universidade do Porto, Praça Gomes Teixeira, Apartado 55142, 4051-401 Porto, Portugal.; Marine and Environmental Sciences Centre (MARE), ESTM, Instituto Politécnico de Leiria, 2050-641 Peniche, Portugal., Guerreiro SFC; Centre for Rapid and Sustainable Product Development (CDRSP), Instituto Politécnico de Leiria, 2030-028 Marinha Grande, Portugal.; Medical Physics Department, Portuguese Institute of Oncology (IPO-Porto), 4200-072 Porto, Portugal.; Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Rua Alfredo Allen 208, 4200-135 Porto, Portugal., Valente JFA; Centre for Rapid and Sustainable Product Development (CDRSP), Instituto Politécnico de Leiria, 2030-028 Marinha Grande, Portugal., Patrício TMF; Centre for Rapid and Sustainable Product Development (CDRSP), Instituto Politécnico de Leiria, 2030-028 Marinha Grande, Portugal., Alves N; Centre for Rapid and Sustainable Product Development (CDRSP), Instituto Politécnico de Leiria, 2030-028 Marinha Grande, Portugal., Mateus A; Centre for Rapid and Sustainable Product Development (CDRSP), Instituto Politécnico de Leiria, 2030-028 Marinha Grande, Portugal., Dias JR; Centre for Rapid and Sustainable Product Development (CDRSP), Instituto Politécnico de Leiria, 2030-028 Marinha Grande, Portugal.
Jazyk: angličtina
Zdroj: Polymers [Polymers (Basel)] 2022 Aug 16; Vol. 14 (16). Date of Electronic Publication: 2022 Aug 16.
DOI: 10.3390/polym14163329
Abstrakt: The pandemic situation caused by coronavirus clearly demonstrated the need for alternatives able to protect the respiratory tract and inactivate the infectious agents. Based on this, antibacterial face-mask filters of polycaprolactone (PCL) dopped with magnesium oxide (MgO) and copper oxide (CuO) nanoparticles (NPs) were produced using an electrospinning technique. A morphological analysis of electrospun meshes evaluated the success of nanoparticles' incorporation as well as the average fibers' diameters (481 ± 272 nm). The performance of electrospun nanofibers was also assessed in terms of tensile strength (0.88 ± 0.25 MPa), water vapor permeability (11,178.66 ± 35.78 g·m -2 ·day -1 ), stability under wet conditions and antibacterial activity according to the standard guidelines. The filters showed structural stability up to 2 h of washing and improved antibacterial activity against Escherichia coli ( E. coli ) and Staphylococcus aureus ( S. aureus ) for optimized concentrations of MgO and CuO NPs. Overall, electrospun meshes with antibacterial activity were successfully developed for advanced filtering applications.
Databáze: MEDLINE
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