Modularity of the Human Musculoskeletal System: The Correlation between Functional Structures by Computer Tools Analysis.

Autor: Della Posta D; Department of Experimental and Clinical Medicine, Anatomy and Histology Section, University of Firenze, L.go Brambilla 3, 50134 Firenze, Italy., Branca JJV; Department of Experimental and Clinical Medicine, Anatomy and Histology Section, University of Firenze, L.go Brambilla 3, 50134 Firenze, Italy., Guarnieri G; Department of Experimental and Clinical Medicine, Anatomy and Histology Section, University of Firenze, L.go Brambilla 3, 50134 Firenze, Italy., Veltro C; Department of Experimental and Clinical Medicine, Anatomy and Histology Section, University of Firenze, L.go Brambilla 3, 50134 Firenze, Italy., Pacini A; Department of Experimental and Clinical Medicine, Anatomy and Histology Section, University of Firenze, L.go Brambilla 3, 50134 Firenze, Italy., Paternostro F; Department of Experimental and Clinical Medicine, Anatomy and Histology Section, University of Firenze, L.go Brambilla 3, 50134 Firenze, Italy.
Jazyk: angličtina
Zdroj: Life (Basel, Switzerland) [Life (Basel)] 2022 Aug 03; Vol. 12 (8). Date of Electronic Publication: 2022 Aug 03.
DOI: 10.3390/life12081186
Abstrakt: Introduction: For many years, anatomical studies have been conducted with a shattered view of the body. Although the study of the different apparatuses provides a systemic view of the human body, the reconstruction of the complex network of anatomical structures is crucial for the understanding of structural and functional integration.
Aim: We used network analysis to investigate the connection between the whole-body osteo-myofascial structures of the human musculoskeletal system.
Materials and Methods: The musculoskeletal network was performed using the aNETomy ® anatomical network with the implementation of the open-source software Cytoscape for data entry.
Results: The initial graph was applied with a network consisting of 2298 body parts (nodes) and 7294 links, representing the musculoskeletal system. Considering the same weighted and unweighted osteo-myofascial network, a different distribution was obtained, suggesting both a topological organization and functional behavior of the network structure.
Conclusions: Overall, we provide a deeply detailed anatomical network map of the whole-body musculoskeletal system that can be a useful tool for the comprehensive understanding of every single structure within the complex morphological organization, which could be of particular interest in the study of rehabilitation of movement dysfunctions.
Databáze: MEDLINE
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