Patterns of Care for Breast Radiotherapy in Italy: Breast IRRadiATA (Italian Repository of Radiotherapy dATA) Feasibility Study.

Autor: Ciabattoni A; Department of Radiation Oncology, Ospedale San Filippo Neri, ASL Roma 1, 00135 Roma, Italy., Gregucci F; Department of Radiation Oncology, Ospedale Generale Regionale 'F. Miulli', Acquaviva delle Fonti, 70021 Bari, Italy., D'Ermo G; Department of Surgery, 'Pietro Valdoni', Universitá di Roma 'La Sapienza', 00185 Roma, Italy.; LILT, Lega Italiana Contro i Tumori, Sede Centrale Via A. Torlonia, 15, 00161 Roma, Italy., Dolfi A; Department of Radiation Oncology, Ospedale San Filippo Neri, ASL Roma 1, 00135 Roma, Italy., Cucciarelli F; Department of Radiation Oncology, Azienda Ospedaliera Ospedali Riuniti Marche Nord, 61029 Ancona, Italy., Palumbo I; Radiation Oncology Section, University of Perugia and Perugia General Hospital, 06123 Perugia, Italy., Borghesi S; Department of Radiation Oncology, Azienda USL Toscana Sud Est, Sede Operativa Valdarno, 52100 Arezzo Valdarno, Italy., Gava A; Department of Radiation Oncology, Azienda Ospedaliera ULSS 9, 31100 Treviso, Italy., Cesaro GM; Department of Radiation Oncology, Azienda Ospedaliera ULSS 9, 31100 Treviso, Italy., Baldissera A; Department of Radiation Oncology, Ospedale Bellaria, 40139 Bologna, Italy., Giammarino D; Department of Radiation Oncology, Azienda Ospedaliera San Camillo Forlanini, 00152 Roma, Italy., Daidone A; Department of Radiation Oncology, Centro San Gaetano, Sede di Bagheria e Sede di Mazzara del Vallo, 35121 Palermo e Trapani, Italy., Maurizi F; Department of Radiation Oncology, Azienda Ospedaliera Ospedali Riuniti Marche Nord, 61029 Pesaro, Italy., Mignogna M; Department of Radiation Oncology, Azienda Ospedaliera USL Toscana Nord Ovest, 56121 Lucca, Italy., Mazzuoli L; Department of Radiation Oncology, Azienda Ospedaliera ASL Viterbo, 01100 Viterbo, Italy., Ravo V; Department of Radiation Oncology, Istituto Nazionale Tumori IRCCS Fondazione Pascale, 80131 Napoli, Italy., Falivene S; Department of Radiation Oncology, Istituto Nazionale Tumori IRCCS Fondazione Pascale, 80131 Napoli, Italy., Pedretti S; Department of Radiation Oncology, ASST Spedali Civili Brescia, 25123 Brescia, Italy., Ippolito E; Department of Radiation Oncology, Università Campus Bio-Medico e Fondazione Campus Bio-Medico, 00128 Roma, Italy., Barbarino R; Department of Radiation Oncology, Fondazione PTV, Policlinico Tor Vergata, 75013 Roma, Italy., di Cristino D; Department of Radiation Oncology, Ospedale San Filippo Neri, ASL Roma 1, 00135 Roma, Italy., Fiorentino A; Department of Radiation Oncology, Ospedale Generale Regionale 'F. Miulli', Acquaviva delle Fonti, 70021 Bari, Italy., Aristei C; Radiation Oncology Section, University of Perugia and Perugia General Hospital, 06123 Perugia, Italy., Ramella S; Department of Radiation Oncology, Università Campus Bio-Medico e Fondazione Campus Bio-Medico, 00128 Roma, Italy., D'Angelillo RM; Department of Radiation Oncology, Fondazione PTV, Policlinico Tor Vergata, 75013 Roma, Italy., Meattini I; Department of Experimental and Clinical Biomedical Sciences 'M. Serio', Department of Oncology, Radiation Oncology Unit, Ospedale Universitario Careggi, Universitá di Firenze, 50134 Firenze, Italy., Iotti C; Radiation Therapy Unit, Azienda USL-IRCCS di Reggio Emilia, 42122 Reggio Emilia, Italy.; AIRO President, AIRO-Associazione Italiana di Radioterapia ed Oncologia Clinica, Piazza della Repubblica 32, 20124 Milano, Italy., Donato V; Department of Radiation Oncology, Azienda Ospedaliera San Camillo Forlanini, 00152 Roma, Italy.; AIRO Past President, AIRO-Associazione Italiana di Radioterapia ed Oncologia Clinica, Piazza della Repubblica 32, 20124 Milano, Italy., Formenti SC; Department of Radiation Oncology, Weill Cornell Medicine-New York Presbyterian Hospital, New York, NY 10065, USA.
Jazyk: angličtina
Zdroj: Cancers [Cancers (Basel)] 2022 Aug 15; Vol. 14 (16). Date of Electronic Publication: 2022 Aug 15.
DOI: 10.3390/cancers14163927
Abstrakt: Aim. Breast IRRADIATA (Italian Repository of RADIotherapy dATA) is a collaborative nationwide project supported by the Italian Society of Radiotherapy and Clinical Oncology (AIRO) and the Italian League Against Cancer (LILT). It focuses on breast cancer (BC) patients treated with radiotherapy (RT) and was developed to create a national registry and define the patterns of care in Italy. A dedicated tool for data collection was created and pilot tested. The results of this feasibility study are reported here. Methods. To validate the applicability of a user-friendly data collection tool, a feasibility study involving 17 Italian Radiation Oncology Centers was conducted from July to October 2021, generating a data repository of 335 BC patients treated between January and March 2020, with a minimum follow-up time of 6 months. A snapshot of the clinical presentation, treatment modalities and radiotherapy toxicity in these patients was obtained. A Data Entry Survey and a Satisfaction Questionnaire were also sent to all participants. Results. All institutions completed the pilot study. Regarding the Data Entry survey, all questions achieved 100% of responses and no participant reported spending more than 10 min time for either the first data entry or for the updating of follow-up. Results from the Satisfaction Questionnaire revealed that the project was described as excellent by 14 centers (82.3%) and good by 3 (17.7%). Conclusion. Current knowledge for the treatment of high-prevalence diseases, such as BC, has evolved toward patient-centered medicine, evidence-based care and real-world evidence (RWE), which means evidence obtained from real-world data (RWD). To this aim, Breast IRRADIATA was developed as a simple tool to probe the current pattern of RT care in Italy. The pilot feasibility of IRRADIATA encourages a larger application of this tool nationwide and opens the way to the assessment of the pattern of care radiotherapy directed to other cancers.
Databáze: MEDLINE
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