| Autor: |
LaVail MM, Gorrin GM, Repaci MA, Thomas LA, Ginsberg HM |
| Jazyk: |
angličtina |
| Zdroj: |
Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 1987 Jul; Vol. 28 (7), pp. 1043-8. |
| Abstrakt: |
Albino mice of different inbred strains have been exposed to constant fluorescent lighting at an illuminance level of 115-130 ft-c for intervals of 1-6 weeks. Under these conditions the photoreceptors in retinas of albino BALB/cByJ mice rapidly degenerate, whereas the photoreceptors in retinas of albino C57BL/6J-c2J mice are remarkably more resistant to light damage. F1 heterozygotes produced from these two strains display an intermediate degree of light-induced degeneration. These findings demonstrate that phenotypically identical populations with different genetic constitutions can show markedly different sensitivities to light, and that genetic factors must now be included as a determinant for the severity of light damage. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
