Applications of elastography in operative neurosurgery: A systematic review.

Autor: Hersh AM; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, United States., Weber-Levine C; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, United States., Jiang K; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, United States., Young L; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, United States., Kerensky M; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, United States., Routkevitch D; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, United States; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, United States., Tsehay Y; Department of Neurosurgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States., Perdomo-Pantoja A; Department of Neurosurgery, Washington University School of Medicine, St. Louis, MO, United States., Judy BF; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, United States., Lubelski D; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, United States., Theodore N; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, United States; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, United States. Electronic address: theodore@jhmi.edu., Manbachi A; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, United States; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Jazyk: angličtina
Zdroj: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia [J Clin Neurosci] 2022 Oct; Vol. 104, pp. 18-28. Date of Electronic Publication: 2022 Aug 04.
DOI: 10.1016/j.jocn.2022.07.019
Abstrakt: Elastography is an imaging technology capable of measuring tissue stiffness and consistency. The technology has achieved widespread use in the workup and management of diseases of the liver, breast, thyroid, and prostate. Although elastography is increasingly being applied in neurosurgery, it has not yet achieved widespread adoption and many clinicians remain unfamiliar with the technology. Therefore, we sought to summarize the range of applications and elastography modalities available for neurosurgery, report its effectiveness in comparison with conventional imaging methods, and offer recommendations. All full-text English-language manuscripts on the use of elastography for neurosurgical procedures were screened using the PubMed/MEDLINE, Embase, Cochrane Library, Scopus, and Web of Science databases. Thirty-two studies were included with 990 patients, including 21 studies on intracranial tumors, 5 on hydrocephalus, 4 on epilepsy, 1 on spinal cord compression, and 1 on adolescent scoliosis. Twenty studies used ultrasound elastography (USE) whereas 12 used magnetic resonance elastography (MRE). MRE studies were mostly used in the preoperative setting for assessment of lesion stiffness, tumor-brain adherence, diagnostic workup, and operative planning. USE studies were performed intraoperatively to guide resection of lesions, determine residual microscopic abnormalities, assess the tumor-brain interface, and study mechanical properties of tumors. Elastography can assist with resection of brain tissue, detection of microscopic lesions, and workup of hydrocephalus, among other applications under investigation. Its sensitivity often exceeds that of conventional MRI and ultrasound for identifying abnormal tissue and lesion margins.
Competing Interests: Declaration of Competing Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Nicholas Theodore receives royalties from and owns stock in Globus Medical. He is a consultant for Globus Medical and has served on scientific advisory board/other office for Globus Medical. The remaining authors have no conflicts of interest to disclose.
(Copyright © 2022. Published by Elsevier Ltd.)
Databáze: MEDLINE
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