The relationship between complete hydatidiform mole and serum Vitamin D level: a prospective case-control study.

Autor:	Gündüz R; Department of Obstetrics and Gynecology, Faculty of Medicine, Dicle University, Diyarbakir, Turkey. ryhn.gunduz@gmail.com., Değer U, Kaplan I, Bayramoğlu Tepe N, Yaman Tunç S, Içen MS, Ağaçayak E, Evsen MS
Jazyk:	angličtina
Zdroj:	European review for medical and pharmacological sciences [Eur Rev Med Pharmacol Sci] 2022 Jul; Vol. 26 (14), pp. 4991-4996.
DOI:	10.26355/eurrev_202207_29285
Abstrakt:	Objective: This study aimed to determine whether or not there was a relationship between complete hydatidiform mole (CHM) and serum Vitamin D level by comparing CHM patients with two control groups and to determine whether or not Vitamin D deficiency is a risk factor for CHM. Patients and Methods: This prospective study included 30 patients diagnosed with CHM (case group), 30 patients in the first trimester of a healthy pregnancy (control group), and 30 healthy non-pregnant subjects (control group). A record was made of serum 25-hydroxyvitamin D (25-OH D vitamin) levels, age, body mass index (BMI), gravida, parity, and the number of abortus. The serum 25-OH D vitamin levels were examined in each group and compared between groups. Results: The 25-OH D vitamin level of all the patients in the study was determined as 11.16±8.64 ng/mL. No significant difference was determined between the groups in respect of 25 OH-D vitamin levels. When comparisons were made between the four subgroups according to the 25-OH-D level, no significant difference was determined between the CHM and control groups. When the patients were separated as obese and non-obese groups, no significant difference was determined between the groups. Conclusions: Severe deficiency, deficiency, or insufficient levels of serum Vitamin D are not thought to be risk factors for CHM patients.
Databáze:	MEDLINE
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