Clinical-epidemiologic variation in patients treated in the first and second wave of COVID-19 in Lambayeque, Peru: A cluster analysis.

Autor:	Valladares-Garrido MJ; Instituto de Evaluación de Tecnologías en Salud e Investigación - IETSI, EsSalud, Lima, Peru; South American Center for Education and Research in Public Health, Universidad Norbert Wiener, Lima, Peru., Failoc-Rojas VE; Instituto de Evaluación de Tecnologías en Salud e Investigación - IETSI, EsSalud, Lima, Peru; Universidad San Ignacio de Loyola, Lima, Peru. Electronic address: virgiliofr@gmail.com., Soto-Becerra P; Instituto de Evaluación de Tecnologías en Salud e Investigación - IETSI, EsSalud, Lima, Peru; Universidad Continental, Huancayo, Peru., Zeña-Ñañez S; Instituto de Evaluación de Tecnologías en Salud e Investigación - IETSI, EsSalud, Lima, Peru; Universidad Continental, Huancayo, Peru., Torres-Roman JS; Facultad de Ciencias de la Salud, Universidad Científica del Sur, Lima, Peru., Fernández-Mogollón JL; Hospital Nacional Almanzor Aguinaga Asenjo, EsSalud, Chiclayo, Peru., Colchado-Palacios IG; Hospital Nacional Almanzor Aguinaga Asenjo, EsSalud, Chiclayo, Peru., Apolaya-Segura CE; Hospital Nacional Almanzor Aguinaga Asenjo, EsSalud, Chiclayo, Peru., Dávila-Gonzales JA; Hospital Nacional Almanzor Aguinaga Asenjo, EsSalud, Chiclayo, Peru., Arce-Villalobos LR; Hospital Nacional Almanzor Aguinaga Asenjo, EsSalud, Chiclayo, Peru., Neciosup-Puican RDP; Hospital Nacional Almanzor Aguinaga Asenjo, EsSalud, Chiclayo, Peru., Calvay-Requejo AG; Hospital Nacional Almanzor Aguinaga Asenjo, EsSalud, Chiclayo, Peru., Maguiña JL; Instituto de Evaluación de Tecnologías en Salud e Investigación - IETSI, EsSalud, Lima, Peru; Facultad de Ciencias de la Salud, Universidad Científica del Sur, Lima, Peru., Apolaya-Segura M; Instituto de Evaluación de Tecnologías en Salud e Investigación - IETSI, EsSalud, Lima, Peru; Facultad de Medicina, Universidad Cesar Vallejo, Chiclayo, Peru., Díaz-Vélez C; Instituto de Evaluación de Tecnologías en Salud e Investigación - IETSI, EsSalud, Lima, Peru; Facultad de Medicina, Universidad Privada Antenor Orrego, Trujillo, Peru.
Jazyk:	angličtina
Zdroj:	International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2022 Oct; Vol. 123, pp. 212-220. Date of Electronic Publication: 2022 Jul 22.
DOI:	10.1016/j.ijid.2022.07.045
Abstrakt:	Objectives: To identify differences in the clinical and epidemiologic characteristics of patients during the first and second waves of the COVID-19 pandemic at the EsSalud Lambayeque health care network, Peru. Methods: An analytical cross-sectional study of 53,912 patients enrolled during the first and second waves of COVID-19 was conducted. Cluster analysis based on clustering large applications (CLARA) was applied to clinical-epidemiologic data presented at the time of care. The two pandemic waves were compared using clinical-epidemiologic data from epidemiologic surveillance. Results: Cluster analysis identified four COVID-19 groups with a characteristic pattern. Cluster 1 included the largest number of participants in both waves, and the participants were predominantly female. Cluster 2 included patients with gastrointestinal, respiratory, and systemic symptoms. Cluster 3 was the "severe" cluster, characterized by older adults and patients with dyspnea or comorbidities (cardiovascular, diabetes, obesity). Cluster 4 included asymptomatic, pregnant, and less severe patients. We found differences in all clinical-epidemiologic characteristics according to the cluster to which they belonged. Conclusion: Using cluster analysis, we identified characteristic patterns in each group. Respiratory, gastrointestinal, dyspnea, anosmia, and ageusia symptoms were higher in the second COVID-19 wave than the first COVID-19 wave. (Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Databáze:	MEDLINE
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