Healing of a chronic ulcer of the lower limb of venous origin with fresh human amniochorionic membrane allograft

Autor: Piamo A; Servicio de Anatomía Patológica, Hospital Maternoinfantil de Amazonas, Puerto Ayacucho, Venezuela. b51amazonas@gmail.com., García M; Servicio de Gineco-obstetricia, Hospital Maternoinfantil de Amazonas, Puerto Ayacucho, Venezuela. biomedica@ins.gov.co., Romero D; Servicio de Enfermería, Ambulatorio 'Jacinto Convit', San Antonio de Cúa, Venezuela. biomedica@ins.gov.co., Ferrer D; Facultad de Ciencias Médicas 'ICBP Victoria de Girón', Universidad de Ciencias Médicas, La Habana, Cuba. biomedica@ins.gov.co.
Jazyk: English; Spanish; Castilian
Zdroj: Biomedica : revista del Instituto Nacional de Salud [Biomedica] 2022 May 01; Vol. 42 (Sp. 1), pp. 17-25. Date of Electronic Publication: 2022 May 01.
DOI: 10.7705/biomedica.6319
Abstrakt: In its fresh state, the amniochorionic membrane contains various multipotential cells, growth factors, and extracellular matrix proteins that contribute to the healing of chronic vascular ulcers. To demonstrate its effectiveness, a fresh human placental membrane allograft was applied to a chronic venous ulcer in the lower limb of an 89-year-old female patient with a 12 x 10 cm ulcerated lesion of 40 years of evolution in the malleolar area of her left lower limb. Sixty days after the graft, the ulcer was healed in 100% of its surface and a light pink scar on the edges indicated possible pigmentation. Fresh human amniochorionic membrane allograft is a therapeutic alternative for the healing of refractory chronic vascular ulcers of the lower extremities.
Databáze: MEDLINE