| Autor: |
Bota VB; Doctoral School of Biology, Faculty of Biology, 'Alexandru Ioan Cuza' University of Iași, 700505 Iași, Romania.; Faculty of Medicine, 'Vasile Goldiș' Western University of Arad, 310414 Arad, Romania.; National Institute for Economic Research 'Costin C. Kiritescu' of the Romanian Academy, Centre for Mountain Economy (CE-MONT), 725700 Suceava, Romania., Neamtu AA; Faculty of Medicine, 'Vasile Goldiș' Western University of Arad, 310414 Arad, Romania.; Doctoral School of Biomedical Sciences, University of Oradea, 410081 Oradea, Romania., Olah NK; SC PlantExtrakt SRL, Rădaia, 407059 Cluj, Romania.; Faculty of Pharmacy, 'Vasile Goldiș' Western University of Arad, 310414 Arad, Romania., Chișe E; Faculty of Pharmacy, 'Vasile Goldiș' Western University of Arad, 310414 Arad, Romania., Burtescu RF; SC PlantExtrakt SRL, Rădaia, 407059 Cluj, Romania., Pripon Furtuna FR; SC PlantExtrakt SRL, Rădaia, 407059 Cluj, Romania., Nicula AS; National Institute for Economic Research 'Costin C. Kiritescu' of the Romanian Academy, Centre for Mountain Economy (CE-MONT), 725700 Suceava, Romania.; Centre for Research on Settlements and Urbanism, Faculty of Geography, Babeș-Bolyai University from Cluj-Napoca, 400006 Cluj-Napoca, Romania., Neamtu C; Faculty of Medicine, 'Vasile Goldiș' Western University of Arad, 310414 Arad, Romania., Maghiar AM; Department of Surgical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410081 Oradea, Romania., Ivănescu LC; Doctoral School of Biology, Faculty of Biology, 'Alexandru Ioan Cuza' University of Iași, 700505 Iași, Romania., Zamfirache MM; Doctoral School of Biology, Faculty of Biology, 'Alexandru Ioan Cuza' University of Iași, 700505 Iași, Romania., Mathe E; Faculty of Medicine, 'Vasile Goldiș' Western University of Arad, 310414 Arad, Romania.; Institute of Nutrition, Faculty of Agricultural and Food Sciences and Environmental Management, University of Debrecen, H-4032 Debrecen, Hungary., Turcuș V; Faculty of Medicine, 'Vasile Goldiș' Western University of Arad, 310414 Arad, Romania.; National Institute for Economic Research 'Costin C. Kiritescu' of the Romanian Academy, Centre for Mountain Economy (CE-MONT), 725700 Suceava, Romania. |
| Abstrakt: |
Tussilago farfara L., a perennial species, is a medicinal herb used in traditional medicine, mainly for the treatment of respiratory tract-related pathology. In traditional Chinese medicine, flower buds are preferred; in Europe, the leaves are used; and in some parts of India, the whole plant is utilized. This preferential usage of the plant organs might be based on differences in the chemical composition due to environmental conditions, along with preferred traditional and cultural approaches. In this article, the impact of pedoclimatic growth conditions on the morpho-anatomical development and phytochemical profile of the plant were studied on T. farfara in the vegetative state, collected from two different locations in the Romanian spontaneous flora, revealing significant variations. Furthermore, the antioxidant profile of the specific extracts from the aerial and subterranean plant parts is also in accordance with these discrepancies. The plant anatomy was assessed histologically by optical microscopy, while the analytical chemistry evaluation was based on LC/MS and spectral methods for the evaluation of the antioxidant and enzyme inhibitory activity. To our knowledge, this is the first comparative analysis contextually reporting on the histology, phenolic profile, antioxidant capacity, and geographical location of the vegetative form of T. farfara . |
