Real-world evaluation of followup strategies after ICD therapies in patients with VT (REFINE-VT).

Autor:	Tran P; Cardiology Registrar University Hospitals Coventry & Warwickshire, Clifford Bridge Road, CV2 2DX., Marshall L; Senior Cardiac Physiologist University Hospitals Coventry & Warwickshire, Clifford Bridge Road, CV2 2DX., Patchett I; Senior Cardiac Physiologist University Hospitals Coventry & Warwickshire, Clifford Bridge Road, CV2 2DX., Salim H; Cardiology Registrar University Hospitals Coventry & Warwickshire, Clifford Bridge Road, CV2 2DX., Yusuf S; Consultant Electrophysiologist University Hospitals Coventry & Warwickshire, Clifford Bridge Road, CV2 2DX., Panikker S; Consultant Electrophysiologist University Hospitals Coventry & Warwickshire, Clifford Bridge Road, CV2 2DX., Kuehl M; Consultant Cardiologist University Hospitals Coventry & Warwickshire, Clifford Bridge Road, CV2 2DX., Osman F; Consultant Electrophysiologist University Hospitals Coventry & Warwickshire, Clifford Bridge Road, CV2 2DX., Banerjee P; Consultant Cardiologist University Hospitals Coventry & Warwickshire, Clifford Bridge Road, CV2 2DX., Randeva H; Director of Research & Development University Hospitals Coventry & Warwickshire, Clifford Bridge Road, CV2 2DX., Dhanjal T; Consultant Electrophysiologist University Hospitals Coventry & Warwickshire, Clifford Bridge Road, CV2 2DX.
Jazyk:	angličtina
Zdroj:	The British journal of cardiology [Br J Cardiol] 2021 Nov 30; Vol. 28 (4), pp. 48. Date of Electronic Publication: 2021 Nov 30 (Print Publication: 2021).
DOI:	10.5837/bjc.2021.048
Abstrakt:	Implantable cardiac defibrillators (ICDs) can prevent sudden cardiac death, but the risk of recurrent ventricular arrhythmia (VA) and ICD shocks persist. Strategies to minimise such risks include medication optimisation, device programming and ventricular tachycardia (VT) ablation. Whether the choice of these interventions at follow-up are influenced by factors such as the type of arrhythmia or ICD therapy remains unclear. To investigate this, we evaluated ICD follow-up strategies in a real-world population with primary and secondary prevention ICDs. REFINE-VT (Real-world Evaluation of Follow-up strategies after Implantable cardiac-defibrillator therapies in patients with Ventricular Tachycardia) is an observational study of 514 ICD recipients recruited between 2018 and 2019. We found that 77 patients (15%) suffered significant VA and/or ICD therapies, of whom 26% experienced a second event; 31% received no intervention. We observed an inconsistent approach to the choice of strategies across different types of arrhythmias and ICD therapies. Odds of intervening were significantly higher if ICD shock was detected compared with anti-tachycardia pacing (odds ratio [OR] 8.4, 95% confidence interval [CI] 1.7 to 39.6, p=0.007). Even in patients with two events, the rate of escalation of antiarrhythmics or referral for VT ablation were as low as patients with single events. This is the first contemporary study evaluating how strategies that reduce the risk of recurrent ICD events are executed in a real-world population. Significant inconsistencies in the choice of interventions exist, supporting the need for a multi-disciplinary approach to provide evidence-based care to this population. Competing Interests: Conflicts of interest None declared. (Copyright © 2021 Medinews (Cardiology) Limited.)
Databáze:	MEDLINE
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