Consistency checks of results from a Monte Carlo code intercomparison for emitted electron spectra and energy deposition around a single gold nanoparticle irradiated by X-rays.

Autor: Rabus H; Physikalisch-Technische Bundesanstalt, Braunschweig and Berlin, Germany.; European Radiation Dosimetry Group (EURADOS) e.V, Neuherberg, Germany., Li WB; Institute of Radiation Medicine, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.; European Radiation Dosimetry Group (EURADOS) e.V, Neuherberg, Germany., Nettelbeck H; Physikalisch-Technische Bundesanstalt, Braunschweig and Berlin, Germany.; European Radiation Dosimetry Group (EURADOS) e.V, Neuherberg, Germany., Schuemann J; Massachusetts General Hospital & Harvard Medical School, Department of Radiation Oncology, Boston, MA, USA.; European Radiation Dosimetry Group (EURADOS) e.V, Neuherberg, Germany., Villagrasa C; Institut de Radioprotection et de Sûreté Nucléaire, Fontenay-Aux-Roses, France.; European Radiation Dosimetry Group (EURADOS) e.V, Neuherberg, Germany., Beuve M; Institut de Physique des 2 Infinis, Université Claude Bernard Lyon 1, Villeurbanne, France.; European Radiation Dosimetry Group (EURADOS) e.V, Neuherberg, Germany., Di Maria S; Centro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa, Bobadela LRS, Portugal.; European Radiation Dosimetry Group (EURADOS) e.V, Neuherberg, Germany., Heide B; Karlsruhe Institute of Technology, Karlsruhe, Germany.; European Radiation Dosimetry Group (EURADOS) e.V, Neuherberg, Germany., Klapproth AP; Institute of Radiation Medicine, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.; TranslaTUM, Klinikum rechts der Isar, Technische Universität München, Munich, Germany., Poignant F; Institut de Physique des 2 Infinis, Université Claude Bernard Lyon 1, Villeurbanne, France.; Present address: National Institute of Aerospace, Hampton, VA, USA., Qiu R; Department of Engineering Physics, Tsinghua University, Beijing, China.; European Radiation Dosimetry Group (EURADOS) e.V, Neuherberg, Germany., Rudek B; Massachusetts General Hospital & Harvard Medical School, Department of Radiation Oncology, Boston, MA, USA.; Present address: Perlmutter Cancer Center, NYU Langone Health, New York City, NY, USA.
Jazyk: angličtina
Zdroj: Radiation measurements [Radiat Meas] 2021 Sep; Vol. 147. Date of Electronic Publication: 2021 Jul 30.
DOI: 10.1016/j.radmeas.2021.106637
Abstrakt: Organized by the European Radiation Dosimetry Group (EURADOS), a Monte Carlo code intercomparison exercise was conducted where participants simulated the emitted electron spectra and energy deposition around a single gold nanoparticle (GNP) irradiated by X-rays. In the exercise, the participants scored energy imparted in concentric spherical shells around a spherical volume filled with gold or water as well as the spectral distribution of electrons leaving the GNP. Initially, only the ratio of energy deposition with and without GNP was to be reported. During the evaluation of the exercise, however, the data for energy deposition in the presence and absence of the GNP were also requested. A GNP size of 50 nm and 100 nm diameter was considered as well as two different X-ray spectra (50 kVp and 100kVp). This introduced a redundancy that can be used to cross-validate the internal consistency of the simulation results. In this work, evaluation of the reported results is presented in terms of integral quantities that can be benchmarked against values obtained from physical properties of the radiation spectra and materials involved. The impact of different interaction cross-section datasets and their implementation in the different Monte Carlo codes is also discussed.
Databáze: MEDLINE
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