Healthcare Predictors of Information Dissemination About Genetic Risks.

Autor:	Henderson V; Fred Hutchinson Cancer Research Center, Public Health Sciences Division, Seattle, WA, USA.; 14681Community Health Sciences Division, University of Illinois Chicago, Chicago, IL, USA., Strayhorn SM; 14621School of Health and Applied Human Sciences, University of North Carolina Wilmington, Wilmington, NC, USA., Bergeron NQ; 14681Community Health Sciences Division, University of Illinois Chicago, Chicago, IL, USA., Strahan DC; 14681Community Health Sciences Division, University of Illinois Chicago, Chicago, IL, USA., Ganschow PS; College of Medicine, University of Illinois Chicago, Chicago, IL, USA.; Cancer Center, University of Illinois Chicago, Chicago, IL, USA., Khanna AS; Department of Behavioral and Social Sciences, Brown University, Providence, RI, USA., Watson K; All of Us Program, National Institutes of Health, Bethesda, MD, USA., Hoskins K; College of Medicine, University of Illinois Chicago, Chicago, IL, USA.; Cancer Center, University of Illinois Chicago, Chicago, IL, USA., Molina Y; 14681Community Health Sciences Division, University of Illinois Chicago, Chicago, IL, USA.; Cancer Center, University of Illinois Chicago, Chicago, IL, USA.
Jazyk:	angličtina
Zdroj:	Cancer control : journal of the Moffitt Cancer Center [Cancer Control] 2022 Jan-Dec; Vol. 29, pp. 10732748221104666.
DOI:	10.1177/10732748221104666
Abstrakt:	Objectives: Despite the benefits of genetic counseling and testing (GCT), utilization is particularly low among African American (AA) women who exhibit breast cancer features that are common in BRCA-associated cancer. Underutilization is especially problematic for AA women who are more likely to die from breast cancer than women from any other race or ethnicity. Due to medical mistrust, fear, and stigma that can be associated with genetic services among racial/ethnic minorities, reliance on trusted social networks may be an impactful strategy to increase dissemination of knowledge about hereditary cancer risk. Informed by the social cognitive theory, the purpose of this study is to determine: 1) which AA patients diagnosed with breast cancer and with identified hereditary risk are sharing information about hereditary risk with their networks; 2) the nature of the information dissemination; and 3) if personal GCT experiences is associated with dissemination of information about hereditary risk. Methods: Among consented participants (n = 100) that completed an interview administered using a 202-item questionnaire consisting of open- and closed-ended questions, 62 patients were identified to be at higher risk for breast cancer. Descriptive statistics, bivariable chi-square, Pearson's exact tests, and regression analyses were conducted to examine differences in characteristics between high-risk participants who disseminated hereditary risk information and participants who did not. Results: Among high-risk participants, 25 (40%) indicated they had disseminated information about hereditary risk to at least one member in their family/friend network and 37 (60%) had not. Receipt of both provider recommendations and receipt of GCT services was associated with greater odds of disseminating information about hereditary risk with networks, OR = 4.53, 95%CI [1.33, 15.50], p = .02. Conclusion: Interventions that increase self-efficacy gained through additional personalized knowledge and experience gained through provider recommendations and by undergoing GCT may facilitate information dissemination among social/familial networks.
Databáze:	MEDLINE
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