Association between ABO and RH blood groups and Hepatitis B virus infection among young Nigerian adults.

Autor:	Oladeinde BH; Department of Medical Laboratory Science, Faculty of Basic Medical Sciences, College of Medical Science, Edo University Iyamho, Edo State, Nigeria., Olaniyan MF; Department of Medical Laboratory Science, Faculty of Basic Medical Sciences, College of Medical Science, Edo University Iyamho, Edo State, Nigeria., Muhibi MA; Department of Medical Laboratory Science, Faculty of Basic Medical Sciences, College of Medical Science, Edo University Iyamho, Edo State, Nigeria., Uwaifo F; Department of Medical Laboratory Science, Faculty of Basic Medical Sciences, College of Medical Science, Edo University Iyamho, Edo State, Nigeria., Richard O; Medical Microbiology Division, Medical Laboratory Services, University of Benin Teaching Hospital, Benin City, Edo State, Nigeria.; School of Medical Laboratory Sciences, University of Benin Teaching Hospital, Benin City, Edo State, Nigeria., Omabe NO; Department of Medical Laboratory Science, Faculty of Basic Medical Sciences, College of Medical Science, Edo University Iyamho, Edo State, Nigeria., Daud A; Department of Medical Laboratory Science, Faculty of Basic Medical Sciences, College of Medical Science, Edo University Iyamho, Edo State, Nigeria., Ozolua OP; Department of Microbiology, Faculty of Science, Edo University Iyamho, Edo State, Nigeria.
Jazyk:	angličtina
Zdroj:	Journal of preventive medicine and hygiene [J Prev Med Hyg] 2022 Apr 26; Vol. 63 (1), pp. E109-E114. Date of Electronic Publication: 2022 Apr 26 (Print Publication: 2022).
DOI:	10.15167/2421-4248/jpmh2022.63.1.1967
Abstrakt:	Background: Several diseases are reported to be associated with ABO/Rh blood groups. Data on the association between ABO and Rh D blood group antigens in the Nigerian population is sparse. This study aimed at determining the prevalence of Hepatitis B Virus (HBV) infection as well as its association with ABO and Rh D antigens among young Nigerian adults. Methods: Whole blood was collected from 496 students and screened for the presence of HBsAg using an immuno-chromatographic technique. The ABO and Rh D antigen status of participants were also determined using standard techniques. Results: In this study, the prevalence of HBV infection was 10/496 (2.10%). Of all factors assessed, only age of participants was identified as a risk factor (P < 0.05) for HBV seropositivity. Over half 257/496 (51.5%) of subjects were of the blood group O type, while 18/496 (3.6%) were of the AB blood type which was the least in occurrence. Rh D negative blood group was observed among 24/496 (4.8%) subjects. Those with the B blood type were observed to have an insignificantly (P > 0.05) higher prevalence of HBV infection. However, with respect to Rh D antigen alone, participants negative for the antigen were observed to have a five times higher risk of acquiring HBV infection than those positive for it (OR = 5.273, 95% CI = 1.056, 26.321, P > 0.05). Combining the ABO and Rh blood group systems, an association (OR = 20.174; P > 0.05) was found to exist between B Rh D negative status and HBV infection. Conclusion: Possession of B antigen without Rh D antigen is associated with increased risk of acquiring HBV infection. Competing Interests: Conflict of interest statement Authors have no conflict of interest to declare. (©2022 Pacini Editore SRL, Pisa, Italy.)
Databáze:	MEDLINE
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