Environmental factors influence the local establishment of Wolbachia in Aedes aegypti mosquitoes in two small communities in central Vietnam.

Autor:	Hien NT; National Institute of Hygiene and Epidemiology, Hanoi, Vietnam., Anh DD; National Institute of Hygiene and Epidemiology, Hanoi, Vietnam., Le NH; National Institute of Hygiene and Epidemiology, Hanoi, Vietnam., Yen NT; National Institute of Hygiene and Epidemiology, Hanoi, Vietnam., Phong TV; National Institute of Hygiene and Epidemiology, Hanoi, Vietnam., Nam VS; National Institute of Hygiene and Epidemiology, Hanoi, Vietnam., Duong TN; National Institute of Hygiene and Epidemiology, Hanoi, Vietnam., Nguyen NB; National Institute of Hygiene and Epidemiology, Hanoi, Vietnam., Huong DTT; National Institute of Hygiene and Epidemiology, Hanoi, Vietnam., Hung LQ; National Institute of Hygiene and Epidemiology, Hanoi, Vietnam., Trinh CNT; National Institute of Hygiene and Epidemiology, Hanoi, Vietnam., Hoang NV; National Institute of Hygiene and Epidemiology, Hanoi, Vietnam., Mai VQ; Institute Pasteur, Nha Trang, Vietnam., Nghia LT; Institute Pasteur, Nha Trang, Vietnam., Dong NT; Institute Pasteur, Nha Trang, Vietnam., Tho LH; Khanh Hoa Health Department, Nha Trang, Vietnam., Kutcher S; World Mosquito Program, Institute of Vector-Borne Disease, Monash University, Clayton, Victoria, 3800, Australia., Hurst TP; World Mosquito Program, Institute of Vector-Borne Disease, Monash University, Clayton, Victoria, 3800, Australia., Montgomery JL; World Mosquito Program, Institute of Vector-Borne Disease, Monash University, Clayton, Victoria, 3800, Australia., Woolfit M; World Mosquito Program, Institute of Vector-Borne Disease, Monash University, Clayton, Victoria, 3800, Australia., Rances E; World Mosquito Program, Institute of Vector-Borne Disease, Monash University, Clayton, Victoria, 3800, Australia., Kyrylos P; World Mosquito Program, Institute of Vector-Borne Disease, Monash University, Clayton, Victoria, 3800, Australia., L Anders K; World Mosquito Program, Institute of Vector-Borne Disease, Monash University, Clayton, Victoria, 3800, Australia., Nguyen L; World Mosquito Program, Institute of Vector-Borne Disease, Monash University, Clayton, Victoria, 3800, Australia., Brown-Kenyon J; World Mosquito Program, Institute of Vector-Borne Disease, Monash University, Clayton, Victoria, 3800, Australia., Caird A; World Mosquito Program, Institute of Vector-Borne Disease, Monash University, Clayton, Victoria, 3800, Australia., McLean BJ; World Mosquito Program, Institute of Vector-Borne Disease, Monash University, Clayton, Victoria, 3800, Australia., Iturbe-Ormaetxe I; World Mosquito Program, Institute of Vector-Borne Disease, Monash University, Clayton, Victoria, 3800, Australia., Ritchie SA; World Mosquito Program, Institute of Vector-Borne Disease, Monash University, Clayton, Victoria, 3800, Australia., O'Neill SL; World Mosquito Program, Institute of Vector-Borne Disease, Monash University, Clayton, Victoria, 3800, Australia., Ryan PA; World Mosquito Program, Institute of Vector-Borne Disease, Monash University, Clayton, Victoria, 3800, Australia.
Jazyk:	angličtina
Zdroj:	Gates open research [Gates Open Res] 2022 Apr 07; Vol. 5, pp. 147. Date of Electronic Publication: 2022 Apr 07 (Print Publication: 2021).
DOI:	10.12688/gatesopenres.13347.2
Abstrakt:	Background: The w Mel strain of Wolbachia has been successfully introduced into Aedes aegypti mosquitoes and subsequently shown to reduce transmission of dengue and other pathogens, under both laboratory and field conditions. Here we describe the entomological outcomes of w Mel Wolbachia mosquito releases in two small communities in Nha Trang City in central Vietnam. Methods: The w Mel strain of Wolbachia was backcrossed into local Aedes aegypti genotype and mosquito releases were undertaken by community members or by staff. Field monitoring was undertaken to track Wolbachia establishment in local Ae. aegypti mosquito populations. Ecological studies were undertaken to assess relationships between environmental factors and the spatial and temporal variability in Wolbachia infection prevalence in mosquitoes. Results: Releases of w Mel Wolbachia Ae. aegypti mosquitoes in two small communities in Nha Trang City resulted in the initial establishment of Wolbachia in the local Ae. aegypti mosquito populations, followed by seasonal fluctuations in Wolbachia prevalence. There was significant small-scale spatial heterogeneity in Wolbachia infection prevalence in the Tri Nguyen Village site, resulting in the loss of w Mel Wolbachia infection in mosquitoes in north and center areas, despite Wolbachia prevalence remaining high in mosquitoes in the south area. In the second site, Vinh Luong Ward, Wolbachia has persisted at a high level in mosquitoes throughout this site despite similar seasonal fluctuations in w Mel Wolbachia prevalence. Conclusion: Seasonal variation in Wolbachia infection prevalence in mosquitoes was associated with elevated temperature conditions, and was possibly due to imperfect maternal transmission of Wolbachia . Heterogeneity in Wolbachia infection prevalence was found throughout one site, and indicates additional factors may influence Wolbachia establishment. Competing Interests: No competing interests were disclosed. (Copyright: © 2022 Hien NT et al.)
Databáze:	MEDLINE
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