Calibration Alignment Sensitivity in Corneal Terahertz Imaging.

Autor: Zarrinkhat F; CommSensLab, Technical University of Catalonia/UPC, 08034 Barcelona, Spain.; Department of Electronics and Nanoengineering, Millilab, Aalto University, 02150 Espoo, Finland., Baggio M; Department of Electronics and Nanoengineering, Millilab, Aalto University, 02150 Espoo, Finland., Lamberg J; Department of Electronics and Nanoengineering, Millilab, Aalto University, 02150 Espoo, Finland., Tamminen A; Department of Electronics and Nanoengineering, Millilab, Aalto University, 02150 Espoo, Finland., Nefedova I; Department of Electronics and Nanoengineering, Millilab, Aalto University, 02150 Espoo, Finland., Ala-Laurinaho J; Department of Electronics and Nanoengineering, Millilab, Aalto University, 02150 Espoo, Finland., Khaled EEM; Department of Electrical Engineering, Assiut University, Assiut 71515, Egypt.; High Institute of Engineering and Technology, Sohag 82524, Egypt., Rius JM; CommSensLab, Technical University of Catalonia/UPC, 08034 Barcelona, Spain., Romeu J; CommSensLab, Technical University of Catalonia/UPC, 08034 Barcelona, Spain., Taylor Z; Department of Electronics and Nanoengineering, Millilab, Aalto University, 02150 Espoo, Finland.
Jazyk: angličtina
Zdroj: Sensors (Basel, Switzerland) [Sensors (Basel)] 2022 Apr 22; Vol. 22 (9). Date of Electronic Publication: 2022 Apr 22.
DOI: 10.3390/s22093237
Abstrakt: Improving the longitudinal modes coupling in layered spherical structure contributes significantly to corneal terahertz sensing, which plays a crucial role in the early diagnosis of cornea dystrophies. Using a steel sphere to calibrate reflection from the cornea sample assists in enhancing the resolution of longitudinal modes. The requirement and challenges toward applying the calibration sphere are introduced and addressed. Six corneas with different properties are spotted to study the effect of perturbations in the calibration sphere in a frequency range from 100 GHz to 600 GHz. A particle-swarm optimization algorithm is employed to quantify corneal characteristics considering cases of accurately calibrated and perturbed calibrated scenarios. For the first case, the study is carried out with signal-to-noise values of 40 dB, 50 dB and 60 dB at waveguide bands WR-5.1, WR-3.4, and WR-2.2. As expected, better estimation is achieved in high-SNR cases. Furthermore, the lower waveguide band is revealed as the most proper band for the assessment of corneal features. For perturbed cases, the analysis is continued for the noise level of 60 dB in the three waveguide bands. Consequently, the error in the estimation of corneal properties rises significantly (around 30%).
Databáze: MEDLINE
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