GC-MS profiling and antibacterial activity of Solanum khasianum leaf and root extracts.

Autor: Chirumamilla P; Department of Biotechnology, Kakatiya University, Warangal, Telangana 506009 India., Dharavath SB; Department of Biotechnology, Kakatiya University, Warangal, Telangana 506009 India., Taduri S; Department of Biotechnology, Kakatiya University, Warangal, Telangana 506009 India.
Jazyk: angličtina
Zdroj: Bulletin of the National Research Centre [Bull Natl Res Cent] 2022; Vol. 46 (1), pp. 127. Date of Electronic Publication: 2022 May 08.
DOI: 10.1186/s42269-022-00818-9
Abstrakt: Background: Solanum khasianum is an important medicinal herb of the Solanaceae family. The present study was focused to determine the bioactive compounds in S. khasianum leaf and root extract by GC-MS analysis and their antibacterial activity by agar well diffusion method.
Results: Sixteen bioactive compounds were detected in leaf extract and thirty-two compounds in root methanolic extract by GC-MS. The major potent compounds identified in leaf and root extracts were heptadecane 9-hexyl (43.65%) and stigmasterol (23.18%). The root extract showed increased antibacterial activity than leaf extract.
Conclusion: These extracts possessed significant antibacterial activity against the tested bacterial isolates in dose-dependent manner. This study provides the phytoconstituents, antibacterial property and scientific evidence for the traditional claim and use of S. khasianum.
Competing Interests: Competing interestsThe authors declare that they have no competing interests.
(© The Author(s) 2022.)
Databáze: MEDLINE
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