Therapeutic approaches and vaccination in fighting COVID-19 infections: A review.

Autor: Adibzadeh S; Medical Biotechnology Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.; Student Research Committee, Pasteur Institute of Iran, Tehran, Iran., Amiri S; Medical Biotechnology Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.; Student Research Committee, Pasteur Institute of Iran, Tehran, Iran., Nia GE; Faculty of Allied Medicine, Cellular and Molecular Research Centre, Iran University of Medical Science, Tehran, Iran.; Department of Basic Oncology, Health Institute of Ege University, Izmir, Turkey., Taleghani MR; Biotechnology Research Institute of Industry and Environment, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran., Bijarpas ZK; Department of Biology, Parand Branch, Islamic Azad University, Tehran, Iran., Maserat N; Department of Biology, Sistan and Balouchestan University, Zahedan, Iran., Maali A; Department of Immunology, Pasteur Institute of Iran, Tehran, Iran.; Department of Medical Biotechnology, School of Allied Medicine, Qazvin University of Medical Sciences, Qazvin, Iran., Azad M; Department of Medical Laboratory Sciences, Faculty of Allied Medicine, Qazvin University of Medical Sciences, Qazvin, Iran., Behzad-Behbahani A; Diagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Jazyk: angličtina
Zdroj: Gene reports [Gene Rep] 2022 Jun; Vol. 27, pp. 101619. Date of Electronic Publication: 2022 May 04.
DOI: 10.1016/j.genrep.2022.101619
Abstrakt: Coronavirus disease 2019 (COVID-19) is a remarkably contagious and pathogenic viral infection arising from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which first appeared in Wuhan, China. For the time being, COVID-19 is not treated with a specific therapy. The Food and Drug Administration (FDA) has approved Remdesivir as the first drug to treat COVID-19. However, many other therapeutic approaches are being investigated as possible treatments for COVID-19. As part of this review, we discussed the development of various drugs, their mechanism of action, and how they might be applied to different cases of COVID-19 patients. Furthermore, this review highlights an update in the emergence of new prophylactic or therapeutic vaccines against COVID-19. In addition to FDA or The World Health Organization (WHO) approved vaccines, we intended to incorporate the latest published data from phase III trials about different COVID-19 vaccines and provide clinical data released on the networks or peer-review journals.
Competing Interests: The authors have no conflicts of interest to declare.
(© 2022 Published by Elsevier Inc.)
Databáze: MEDLINE
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