Metastatic Pheochromocytoma Diagnosed with 131 I-MIBG SPECT/CT Imaging in a Patient with Pathogenic VHL Mutation.

Autor: Vankadari K; Department of Nuclear Medicine, Yashoda Hospital, Secunderabad, Telangana, India., Boddula R; Department of Endocrinology, Yashoda Hospital, Secunderabad, Telangana, India., Hegde AG; Department of Endocrinology, Yashoda Hospital, Secunderabad, Telangana, India., Chinte C; Department of Endocrinology, Yashoda Hospital, Secunderabad, Telangana, India.
Jazyk: angličtina
Zdroj: World journal of nuclear medicine [World J Nucl Med] 2022 Apr 30; Vol. 21 (1), pp. 73-75. Date of Electronic Publication: 2022 Apr 30 (Print Publication: 2022).
DOI: 10.1055/s-0042-1746177
Abstrakt: Pheochromocytoma is a rare catecholamine secreting neuroendocrine tumor arising from chromaffin cells of adrenal medulla with approximate prevalence of 0.1 to 0.6% in patients suffering from hypertension. Hypertensive control followed by surgical resection remains the primary treatment of choice. Although it is considered a slow growing benign tumor, it rarely leads to recurrence of tumor in the lymph nodes, liver, and lungs. Association of benign pheochromocytoma with familial or de novo Von Hippel-Lindau (VHL) mutations is well reported in literature. Here, we report a case of metastatic pheochromocytoma arising from commonly seen benign VHL mutation.
Competing Interests: Conflict of Interest None declared.
(World Association of Radiopharmaceutical and Molecular Therapy (WARMTH). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ).)
Databáze: MEDLINE
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