Intralesional Avirulent Bacillus Calmette-Guérin Injection as a Promising Method for the Treatment of Tuberculosis Verrucosa Cutis.

Autor: Gündüz Ö; Department of Dermatology, University of Kirikkale, Kirikkale, Turkey., Koçak G; Department of Dermatology and Venerology, İstanbul Başakşehir Çam ve Sakura City Hospital, Istanbul, Turkey., Kaçmaz B; Department of Clinical Microbiology and Infectious Diseases, University of Kirikkale, Kirikkale, Turkey., Devrim T; Department of Clinical Pathology, University of Kirikkale, Kirikkale, Turkey., Şimşek H; Department of Clinical Microbiology, Yozgat Bozok University, Yozgat, Turkey.; Department of Microbiology Reference Laboratories and Biological Products, National Tuberculosis Reference Laboratory, General Directorate of Public Health, Turkish Ministry of Health, Ankara, Turkey.
Jazyk: angličtina
Zdroj: Case reports in dermatology [Case Rep Dermatol] 2022 Mar 21; Vol. 14 (1), pp. 49-54. Date of Electronic Publication: 2022 Mar 21 (Print Publication: 2022).
DOI: 10.1159/000523797
Abstrakt: Cutaneous involvement is a relatively uncommon manifestation of tuberculosis (TB), particularly outside the endemic regions. Cutaneous TB manifests itself in various clinical forms, depending on the host's immune status and mode of transmission. Nonetheless, the same treatment regimen is recommended for every subtype. Tuberculosis verrucosa cutis (TBVC) is a specific subgroup in which the affected persons are usually healthy adults who are vaccinated or exposed to mycobacteria during their occupational activities. These patients have the ability to launch a strong cellular immune reaction against mycobacteria. In this article, we present an elderly patient with a 4-year history of TBVC who was treated with intralesional injection of avirulent Bacillus Calmette-Guérin (BCG) and report our clinical observation on the inflammatory and healing process of the patient's lesion following the intralesional BCG injection.
Competing Interests: The authors have no conflicts of interest to declare.
(Copyright © 2022 by S. Karger AG, Basel.)
Databáze: MEDLINE
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