The use of autologous epidermal grafts for diabetic foot ulcer emergencies: A clinical study.

Autor: Saydam M; Department of General Surgery, Institute of Health Sciences Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara-Turkey., Yılmaz KB; Department of General Surgery, Institute of Health Sciences, Gülhane Training and Research Hospital, Ankara-Turkey., Bostancı MT; Department of General Surgery, Institute of Health Sciences Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara-Turkey., Turan M; Department of General Surgery, Institute of Health Sciences, Gülhane Training and Research Hospital, Ankara-Turkey., Akıncı M; Department of General Surgery, Institute of Health Sciences, Gülhane Training and Research Hospital, Ankara-Turkey., Yılmaz İ; Department of General Surgery, Institute of Health Sciences Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara-Turkey., Öztas M; Department of General Surgery, Institute of Health Sciences, Gülhane Training and Research Hospital, Ankara-Turkey., Güven HE; Department of General Surgery, Institute of Health Sciences, Gülhane Training and Research Hospital, Ankara-Turkey.
Jazyk: angličtina
Zdroj: Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES [Ulus Travma Acil Cerrahi Derg] 2022 Mar; Vol. 28 (3), pp. 262-267.
DOI: 10.14744/tjtes.2020.68202
Abstrakt: Background: There are various surgical and invasive treatment systems such as conservative skin grafts and autologous epider-mal grafting (AEG) for diabetic foot ulcers. This study aims to evaluate the feasibility of using a novel epidermal graft harvesting system in diabetic foot ulcer emergencies.
Methods: A retrospective clinical study was conducted with 15 diabetic foot ulcer patients, and after written and signed consent forms were taken, AEG system was applied to all patients. All of the clinical data of the patients such as their American Society of Anesthesiologists (ASA) Physical Status Classification System scores, size of pre-application wound area (cm2), time to complete re-epithelization of the wound, pain scores using the visual analog scale (VAS) for both donor and recipient sites, changes in size of wound, complete dermal response time, and patients' demographics, comorbidities were recorded. The age, gender, pre-post appli-cation wound area (cm2), time of healing, ASA, and VAS variables were compared each other and analyzed statistically. P<0.05 was considered as statistically significant.
Results: The mean of time for complete wound healing was 5.9 (range 4-8) weeks. There was no statistically difference between recipient wound size and patient's age; size of both types of wounds (cm2) and time (weeks) for complete reduction for both types of wounds; and time to complete both types of wound healing and gender (p=0.509, 0.788, and 0.233, respectively). ASA scores did not impact the time required for complete healing of the wound (p=0.749).
Conclusion: The current study has tried to evaluate the efficacy of the AEG system in a homogenous population with diabetic foot ulcers. An epidermal harvesting system may be used effectively and safely in patients with diabetic foot ulcer emergencies.
Databáze: MEDLINE