Low numbers of COVID-19 in Swedish pediatric oncology patients during the first pandemic year despite an open society.

Autor: Sundberg E; Department of Children's Oncology and Hematology, Uppsala University Hospital, Uppsala, Sweden.; Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden., Georgantzi K; Division of Pediatric Hematology-Oncology, Tema Barn, Astrid Lindgren Children's Hospital, Stockholm, Sweden., Langenskiöld C; Children's Cancer Centre, Queen Silvia Children's Hospital, Gothenburg, Sweden., Król L; Division of Pediatric Hematology-Oncology, Skåne University Hospital, Lund, Sweden., Nilsson F; Division of Pediatric Hematology-Oncology, Umeå University Hospital, Umeå, Sweden., Vogt H; Crown Princess Victoria's Child and Youth Hospital, Division of Pediatric Hematology-Oncology B153, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden., Palle J; Department of Children's Oncology and Hematology, Uppsala University Hospital, Uppsala, Sweden., Ek T; Children's Cancer Centre, Queen Silvia Children's Hospital, Gothenburg, Sweden., Nilsson A; Division of Pediatric Hematology-Oncology, Tema Barn, Astrid Lindgren Children's Hospital, Stockholm, Sweden.; Department of Women's and Children's Health, Karolinska Institutet, Solna, Sweden.
Jazyk: angličtina
Zdroj: Pediatric blood & cancer [Pediatr Blood Cancer] 2022 Oct; Vol. 69 (10), pp. e29750. Date of Electronic Publication: 2022 Apr 29.
DOI: 10.1002/pbc.29750
Abstrakt: Background: Sweden adopted a different strategy than many other countries to combat the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic and kept most schools open. Initial reports from China suggested that coronavirus disease 2019 (COVID-19) was milder in children compared to adults, but there was a lack of data from immunocompromised children. Therefore, we investigated the rate of verified SARS-CoV-2 infections in our Swedish pediatric oncology patients.
Procedure: This was a multicenter retrospective study. A questionnaire including patient data as well as SARS-CoV-2 data was sent to the six Swedish childhood cancer centers in May 2021.
Results: During the first pandemic year, 49 patients were identified as SARS-CoV-2 positive, and 22 (45%) children were hospitalized with COVID-19. Two children needed intensive care, but no COVID-19-related deaths were reported. Most patients (n = 36, 73%) were on active chemotherapy treatment and 23 children (49%) attended school or daycare at least part-time. Half of the SARS-CoV-2-positive patients experienced a delay in cancer treatment.
Conclusions: Despite the rapid spread of SARS-CoV-2 in Sweden, without a strict lockdown of the society, the number of nationally reported pediatric oncology patients with polymerase chain reaction (PCR)-verified infection was low, and the majority of children had mild disease. Our data show that treatment interruptions occurred frequently and this should clearly be avoided for the coming years.
(© 2022 The Authors. Pediatric Blood & Cancer published by Wiley Periodicals LLC.)
Databáze: MEDLINE
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