Management and outcomes of acute myocardial infarction in patients with preexisting heart failure: an analysis of 2 million patients from the national inpatient sample.

Autor:	Abramov D; Division of Cardiology, Department of Medicine, Loma Linda Health, Loma Linda, CA, USA., Kobo O; Keele Cardiovascular Research Group, Keele University, Keele, UK.; Department of Cardiology, Hillel Yaffe Medical Center, Hadera, Israel., Mohamed M; Keele Cardiovascular Research Group, Keele University, Keele, UK.; Department of Cardiology, Royal Stoke Hospital, Stoke on Trent, UK., Roguin A; Department of Cardiology, Hillel Yaffe Medical Center, Hadera, Israel., Osman M; Knight Cardiovascular Institute, Oregon Health & Science University, Portland, OR, USA., Patel B; Division of Cardiology, West Virginia University School of Medicine, Morgantown, WV, USA., Parwani P; Division of Cardiology, Department of Medicine, Loma Linda Health, Loma Linda, CA, USA., Alraies C; Detroit Medical Center, Wayne State University, MI, USA., Sauer AJ; Department of Cardiovascular medicine, University of Kansas Medical Center, Kansas City, KS, USA., Van Spall HGC; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.; Population Health Research Institute, Hamilton, Ontario, Canada., Mamas MA; Keele Cardiovascular Research Group, Keele University, Keele, UK.; Department of Cardiology, Royal Stoke Hospital, Stoke on Trent, UK.
Jazyk:	angličtina
Zdroj:	Expert review of cardiovascular therapy [Expert Rev Cardiovasc Ther] 2022 Mar; Vol. 20 (3), pp. 233-240. Date of Electronic Publication: 2022 Mar 31.
DOI:	10.1080/14779072.2022.2058931
Abstrakt:	Background: Inpatient management and outcomes of patients presenting with acute myocardial infarction (AMI) with a history of heart failure (HF) have not been well characterized. Methods: Hospitalizations for AMI from the Nationwide Inpatient Sample (2015-2018) were categorized according to a preexisting diagnosis of HF with preserved ejection fraction (HFpEF), reduced ejection fraction (HFrEF), or absence of HF. Utilization of invasive management and in-hospital outcomes were analyzed. Results: Among 2,434,639 hospitalizations with an AMI, 19.8% had a history of HFrEF and 11.9% had a history of HFpEF. Coronary angiography and PCI respectively were performed significantly less among patients with HF (36.6% and 17.4% in HFpEF, 51.1% and 24.6% in HFrEF, and 64.4% and 42.3% among patients without HF, all p < 0.0001). Mortality was more common among patients with HFrEF (10.3%) and HFpEF (8.3%) when compared to patients without a history of HF (6.4%), p < 0.0001. Conclusion: HF is a common preexisting comorbidity among patients presenting with AMI and is associated with lower utilization of invasive procedures and higher complications including mortality, particularly among those with HFrEF.
Databáze:	MEDLINE
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