Epidemiology of COVID-19 and effect of public health interventions, Chennai, India, March-October 2020: an analysis of COVID-19 surveillance system.

Autor: M J; Greater Chennai Corporation, Government of Tamil Nadu, Chennai, Tamil Nadu, India., Ganeshkumar P; Division of Epidemiology, ICMR - National Institute of Epidemiology, Chennai, Tamil Nadu, India., Kaur P; Division of Non-communicable Diseases, ICMR - National Institute of Epidemiology, Chennai, Tamil Nadu, India kprabhdeep@gmail.com., Masanam Sriramulu H; Greater Chennai Corporation, Government of Tamil Nadu, Chennai, Tamil Nadu, India., Sakthivel M; Field Epidemiology Training Program, ICMR - National Institute of Epidemiology, Chennai, Tamil Nadu, India., Rubeshkumar P; Field Epidemiology Training Program, ICMR - National Institute of Epidemiology, Chennai, Tamil Nadu, India., Raju M; Field Epidemiology Training Program, ICMR - National Institute of Epidemiology, Chennai, Tamil Nadu, India., Murugesan L; Greater Chennai Corporation, Government of Tamil Nadu, Chennai, Tamil Nadu, India., Ganapathi R; Greater Chennai Corporation, Government of Tamil Nadu, Chennai, Tamil Nadu, India., Srinivasan M; Greater Chennai Corporation, Government of Tamil Nadu, Chennai, Tamil Nadu, India., Sukumar A; Division of Non-communicable Diseases, ICMR - National Institute of Epidemiology, Chennai, Tamil Nadu, India., Ilangovan K; Field Epidemiology Training Program, ICMR - National Institute of Epidemiology, Chennai, Tamil Nadu, India., Reddy M; Greater Chennai Corporation, Government of Tamil Nadu, Chennai, Tamil Nadu, India., Shanmugam D; Greater Chennai Corporation, Government of Tamil Nadu, Chennai, Tamil Nadu, India., Govindasamy P; Greater Chennai Corporation, Government of Tamil Nadu, Chennai, Tamil Nadu, India., Murhekar M; Division of Epidemiology, ICMR - National Institute of Epidemiology, Chennai, Tamil Nadu, India.
Jazyk: angličtina
Zdroj: BMJ open [BMJ Open] 2022 Mar 14; Vol. 12 (3), pp. e052067. Date of Electronic Publication: 2022 Mar 14.
DOI: 10.1136/bmjopen-2021-052067
Abstrakt: Objectives: To describe the public health strategies and their effect in controlling the COVID-19 pandemic from March to October 2020 in Chennai, India.
Setting: Chennai, a densely populated metropolitan city in Southern India, was one of the five cities which contributed to more than half of the COVID-19 cases in India from March to May 2020. A comprehensive community-centric public health strategy was implemented for controlling COVID-19, including surveillance, testing, contact tracing, isolation and quarantine. In addition, there were different levels of restrictions between March and October 2020.
Participants: We collected the deidentified line list of all the 192 450 COVID-19 cases reported from 17 March to 31 October 2020 in Chennai and their contacts for the analysis. We defined a COVID-19 case based on the real-time reverse transcriptase-PCR (RT-PCR) positive test conducted in one of the government-approved labs.
Outcome Measures: The primary outcomes of interest were incidence of COVID-19 per million population, case fatality ratio (CFR), deaths per million, and the effective reproduction number (R t ). We also analysed the surveillance, testing, contact tracing and isolation indicators.
Results: Of the 192 450 RT-PCR confirmed COVID-19 cases reported in Chennai from 17 March to 31 October 2020, 114 889 (60%) were males. The highest incidence was 41 064 per million population among those 61-80 years. The incidence peaked during June 2020 at 5239 per million and declined to 3627 per million in October 2020. The city reported 3543 deaths, with a case fatality ratio of 1.8%. In March, R t was 4.2, dropped below one in July and remained so until October, even with the relaxation of restrictions.
Conclusion: The combination of public health strategies might have contributed to controlling the COVID-19 epidemic in a large, densely populated city in India. We recommend continuing the test-trace-isolate strategy and appropriate restrictions to prevent resurgence.
Competing Interests: Competing interests: Support from the Health and Family Welfare Department, Government of Tamil Nadu, India.
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Databáze: MEDLINE