Molecular epidemiology of the SARS-CoV-2 variant Omicron BA.2 sub-lineage in Denmark, 29 November 2021 to 2 January 2022.

Autor: Fonager J; Virus Research and Development Laboratory, Virus and Microbiological Special Diagnostics, Statens Serum Institut, Copenhagen, Denmark., Bennedbæk M; Virus Research and Development Laboratory, Virus and Microbiological Special Diagnostics, Statens Serum Institut, Copenhagen, Denmark., Bager P; Infectious Disease Preparedness, Statens Serum Institut, Copenhagen, Denmark., Wohlfahrt J; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Ellegaard KM; Department of Bacteria, Parasites, and Fungi, Statens Serum Institut, Copenhagen, Denmark., Ingham AC; Department of Bacteria, Parasites, and Fungi, Statens Serum Institut, Copenhagen, Denmark., Edslev SM; Department of Bacteria, Parasites, and Fungi, Statens Serum Institut, Copenhagen, Denmark., Stegger M; Department of Bacteria, Parasites, and Fungi, Statens Serum Institut, Copenhagen, Denmark., Sieber RN; Department of Bacteria, Parasites, and Fungi, Statens Serum Institut, Copenhagen, Denmark., Lassauniere R; Virus Research and Development Laboratory, Virus and Microbiological Special Diagnostics, Statens Serum Institut, Copenhagen, Denmark., Fomsgaard A; Virus Research and Development Laboratory, Virus and Microbiological Special Diagnostics, Statens Serum Institut, Copenhagen, Denmark., Lillebaek T; International Reference Laboratory of Mycobacteriology, Statens Serum Institut, Copenhagen, Denmark.; Global Health Section, University of Copenhagen, Copenhagen, Denmark., Svarrer CW; Department of Bacteria, Parasites, and Fungi, Statens Serum Institut, Copenhagen, Denmark., Møller FT; Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark., Møller CH; Infectious Disease Preparedness, Statens Serum Institut, Copenhagen, Denmark., Legarth R; Infectious Disease Preparedness, Statens Serum Institut, Copenhagen, Denmark., Sydenham TV; Department of Clinical Microbiology, Odense University Hospital, Denmark., Steinke K; Department of Clinical Microbiology, Odense University Hospital, Denmark., Paulsen SJ; Department of Clinical Microbiology, Copenhagen University Hospital Amager-Hvidovre, Hvidovre, Denmark., Castruita JAS; Department of Clinical Microbiology, Copenhagen University Hospital Amager-Hvidovre, Hvidovre, Denmark., Schneider UV; Department of Clinical Microbiology, Copenhagen University Hospital Amager-Hvidovre, Hvidovre, Denmark., Schouw CH; Department of Clinical Microbiology, Zealand University Hospital, Køge, Denmark., Nielsen XC; Department of Clinical Microbiology, Zealand University Hospital, Køge, Denmark., Overvad M; Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark., Nielsen RT; Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark., Marvig RL; Center for Genomic Medicine, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark., Pedersen MS; Department of Clinical Microbiology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark., Nielsen L; Department of Clinical Microbiology, Copenhagen University Hospital-Herlev and Gentofte, Herlev, Denmark., Nilsson LL; Department of Clinical Microbiology, Copenhagen University Hospital-Herlev and Gentofte, Herlev, Denmark., Bybjerg-Grauholm J; Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark., Tarpgaard IH; Clinical Microbiology Department, Aarhus University Hospital, Aarhus, Denmark., Ebsen TS; Clinical Microbiology Department, Aarhus University Hospital, Aarhus, Denmark., Lam JUH; Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark., Gunalan V; Virus Research and Development Laboratory, Virus and Microbiological Special Diagnostics, Statens Serum Institut, Copenhagen, Denmark., Rasmussen M; Virus Research and Development Laboratory, Virus and Microbiological Special Diagnostics, Statens Serum Institut, Copenhagen, Denmark.
Jazyk: angličtina
Zdroj: Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin [Euro Surveill] 2022 Mar; Vol. 27 (10).
DOI: 10.2807/1560-7917.ES.2022.27.10.2200181
Abstrakt: Following emergence of the SARS-CoV-2 variant Omicron in November 2021, the dominant BA.1 sub-lineage was replaced by the BA.2 sub-lineage in Denmark. We analysed the first 2,623 BA.2 cases from 29 November 2021 to 2 January 2022. No epidemiological or clinical differences were found between individuals infected with BA.1 versus BA.2. Phylogenetic analyses showed a geographic east-to-west transmission of BA.2 from the Capital Region with clusters expanding after the Christmas holidays. Mutational analysis shows distinct differences between BA.1 and BA.2.
Databáze: MEDLINE