Consensus on COVID-19 Vaccination in Pediatric Oncohematological Patients, on Behalf of Infectious Working Group of Italian Association of Pediatric Hematology Oncology.

Autor: Cesaro S; Pediatric Hematology Oncology Unit, Department of Mother and Child, Azienda Ospedaliera Universitaria Integrata, 37100 Verona, Italy., Muggeo P; Pediatric Oncology-Hematology Unit, Department of Pediatrics, Azienda Ospedaliero Universitria Policlinico, 70120 Bari, Italy., Zama D; Pediatric Oncology and Hematology Unit 'Lalla Seràgnoli', Pediatric Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Azienda Ospedaliero-Universitaria di Bologna, 40100 Bologna, Italy., Cellini M; Pediatric Oncology-Hematology Unit, Modena University Hospital, 41100 Modena, Italy., Perruccio K; Pediatric Oncology-Hematology Unit, Santa Maria della Misericordia Hospital, 06100 Perugia, Italy., Colombini A; Department of Pediatrics, Ospedale San Gerardo, University of Milano-Bicocca, 20900 Monza, Italy., Carraro F; Division of Paediatric Onco-Haematology, Stem Cell Transplantation and Cellular Therapy, Città della Salute e della Scienza Hospital, 10100 Turin, Italy., Petris MG; Hematology Oncology Division, Department of Women's and Children's Health, University of Padova, 35100 Padova, Italy., Petroni V; Division of Pediatric Hematology and Oncology, Ospedale G. Salesi, 60100 Ancona, Italy., Mascarin M; Adolescent and Young Adult Oncology and Pediatric Radiotherapy Unit, CRO-Centro di Riferimento Oncologico di Aviano, Istituto di Ricovero e Cura a Carattere Scientifico, 33081 Aviano, Italy., Baccelli F; Pediatric Oncology and Hematology Unit 'Lalla Seràgnoli', Pediatric Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Azienda Ospedaliero-Universitaria di Bologna, 40100 Bologna, Italy., Soncini E; Pediatric Oncohematology and Bone Marrow Transplant Unit, Children's Hospital, Spedali Civili, 25100 Brescia, Italy., Mura R; Pediatric Oncology Unit, Azienda Ospedaliera Brotzu, 09100 Cagliari, Italy., La Spina M; Pediatric Hematology and Oncology Unit-AOU Policlinico 'Rodolico-San Marco', University of Catania, 95100 Catania, Italy., Decembrino N; Pediatric Hematology and Oncology Unit-AOU Policlinico 'Rodolico-San Marco', University of Catania, 95100 Catania, Italy., Burnelli R; Pediatric Onco-Hematology Unit, Sant'Anna Hospital, 44100 Ferrara, Italy., Frenos S; Division of Pediatric Oncology/Hematology, Meyer University Children's Hospital, 50100 Florence, Italy., Castagnola E; Istituto di Ricovero e Cura a Carattere Scientifico, Istituto Giannina Gaslini, 16100 Genova, Italy., Faraci M; Istituto di Ricovero e Cura a Carattere Scientifico, Istituto Giannina Gaslini, 16100 Genova, Italy., Meazza C; Pediatric Oncology Unit, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico, Istituto Nazionale dei Tumori, 20100 Milan, Italy., Barzaghi F; Pediatric Immunohematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, 20100 Milan, Italy., D'Amico MR; Department of Pediatric Hemato-Oncology, AORN Santobono-Pausilipon, 80100 Naples, Italy., Capasso M; Department of Pediatric Hemato-Oncology, AORN Santobono-Pausilipon, 80100 Naples, Italy., Calore E; Hematology Oncology Division, Department of Women's and Children's Health, University of Padova, 35100 Padova, Italy., Ziino O; Department of Pediatric Hemato-Oncology, ARNAS Ospedali Civico, G. Di Cristina, 90100 Palermo, Italy., Barone A; Pediatric Onco-Hematology Unit, Pediatric Clinic, Pietro Barilla Children's Hospital, University of Parma, 43100 Parma, Italy., Compagno F; Pediatric Hematology/Oncology Unit, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy., Luti L; Pediatric Onco-Hematology Unit, Pisa University Hospital, 56100 Pisa, Italy., Galaverna F; Department of Pediatric Hematology and Oncology, Bambino Gesù Children's Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), 00100 Rome, Italy., De Santis R; Hemato-Oncology Unit, Department of Pediatrics, 'Casa Sollievo della Sofferenza' Hospital, 71013 San Giovanni Rotondo, Italy., Brescia L; Hemato-Oncology Unit, SS. Annunziata Hospital, 74100 Taranto, Italy., Meneghello L; U.O.M. Pediatria Ospedale S. Chiara, 38100 Trento, Italy., Petrone A; U.O.M. Pediatria Ospedale S. Chiara, 38100 Trento, Italy., Giurici N; Pediatric Hematology-Oncology, Institute for Maternal and Child Health IRCCS 'Burlo Garofolo', 34100 Trieste, Italy., Onofrillo D; Paediatric Haemato-Oncology Unit, Hematology Department, Hospital of Pescara, 65100 Pescara, Italy., Schumacher F; Pediatric Oncohematology and Bone Marrow Transplant Unit, Children's Hospital, Spedali Civili, 25100 Brescia, Italy., Mercolini F; Pediatric Onco-Hematology Unit, Department of Pediatrics, Hospital of Bolzano, 39100 Bolzano, Italy.
Jazyk: angličtina
Zdroj: Journal of clinical medicine [J Clin Med] 2022 Feb 24; Vol. 11 (5). Date of Electronic Publication: 2022 Feb 24.
DOI: 10.3390/jcm11051235
Abstrakt: Vaccines represent the best tool to prevent the severity course and fatal consequences of the pandemic by the new Coronavirus 2019 infection (SARS-CoV-2). Considering the limited data on vaccination of pediatric oncohematological patients, we developed a Consensus document to support the Italian pediatric hematological oncological (AIEOP) centers in a scientifically correct communication with families and patients and to promote vaccination. The topics of the Consensus were: SARS-CoV-2 infection and disease (COVID-19) in the pediatric subjects; COVID-19 vaccines (type, schedule); who and when to vaccinate; contraindications and risk of serious adverse events; rare adverse events; third dose and vaccination after COVID-19; and other general prevention measures. Using the Delphi methodology for Consensus, 21 statements and their corresponding rationale were elaborated and discussed with the representatives of 31 centers, followed by voting. A high grade of Consensus was obtained on topics such as the potential risk of severe COVID-19 outcome in pediatric oncohematological patients, the need for vaccination as a preventative measure, the type, schedule and booster dose of vaccine, the eligibility of the patients for vaccination, and the timing, definition, and management of contraindications and serious adverse events, and other general prevention measures. All 21 of the statements were approved. This consensus document highlights that children and adolescents affected by hematological and oncological diseases are a fragile category. Vaccination plays an important role to prevent COVID-19, to permit the regular administration of chemotherapy or other treatments, to perform control visits and hospital admissions, and to prevent treatment delays.
Databáze: MEDLINE
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