Relation between lipid profile, blood pressure and retinopathy in diabetic patients in King Abdulaziz University hospital: a retrospective record review study.

Autor: Alattas K; Department of Ophthalmology, College of Medicine, King Abdulaziz University Hospital, Jedddah, Saudi Arabia., Alsulami DW; Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia. Dr.dania2030@gmail.com., Alem RH; Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Alotaibi FS; Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Alghamdi BA; Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Baeesa LS; Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Jazyk: angličtina
Zdroj: International journal of retina and vitreous [Int J Retina Vitreous] 2022 Mar 09; Vol. 8 (1), pp. 20. Date of Electronic Publication: 2022 Mar 09.
DOI: 10.1186/s40942-022-00366-4
Abstrakt: Background: Diabetic retinopathy (DR) is a major cause of blindness worldwide, threatening the vision of approximately 10% of patients with diabetes. Many studies have demonstrated that intensive control of the risk factors for DR is essential to reduce the onset and progression of DR. Currently, the relationship between lipid profile and DR is still unclear, especially in Saudi Arabia. We aimed to assess the correlation between both the development and severity of DR with lipid profile and blood pressure among the diabetic patients at the King Abdul-Aziz University hospital in Jeddah, Saudi Arabia.
Methods: This was a retrospective record review study of 298 diabetic patients diagnosed with DR. Retinal findings were correlated to serum lipids levels using univariate, bivariate, and multivariate analysis.
Results: This study included 298 participants with DR. Triglyceride levels, systolic blood pressure, low-density lipoprotein cholesterol levels, and presence of macular edema were significantly associated with DR progression (P = 0.012, P = 0.001, P = 0.002). Other parameters, including total cholesterol, high-density lipoprotein cholesterol, HbA1C, body mass index, age, were not significantly associated with DR.
Conclusion: Elevation in serum triglyceride levels and systolic blood pressure showed a statically significant association with diabetic retinopathy. Controlling these factors may help preventing progression and occurrence of diabetic retinopathy among diabetic patients.
(© 2022. The Author(s).)
Databáze: MEDLINE
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