Microbiological investigation study for Apis mellifera yemenitica and Apis mellifera carnica bee venoms on selected bacterial strains.

Autor: Alajmi RA; Department of Zoology, College of Science, King Saud University, Riyadh, 11495, Saudi Arabia. ralajmi@ksu.edu.sa., Barakat IAH; Cell Biology Department, National Research Center, Giza, Egypt., Alfozan L; Department of Zoology, College of Science, King Saud University, Riyadh, 11495, Saudi Arabia., Mahmoud A; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.; Department of Medicinal Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt., Layqah L; Department of Research Office, King Abdullah International Medical Research Center, Ministry of National Guard, Riyadh, Saudi Arabia., Yehia HM; Department of Food Science and Nutrition, College of Food and Agriculture Sciences, King Saud University, Riyadh, 11451, Saudi Arabia., Metwally DM; Department of Parasitology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, 44519, Egypt. mdbody7@yahoo.com.
Jazyk: angličtina
Zdroj: Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] [Braz J Microbiol] 2022 Jun; Vol. 53 (2), pp. 709-714. Date of Electronic Publication: 2022 Mar 03.
DOI: 10.1007/s42770-021-00656-3
Abstrakt: Bees are one of the ancient and the most social insects worldwide. They are of great economic and medical importance. Bee venom (BV) has many therapeutic effects and has been used since ancient times for the treatment of many diseases. The present study aimed to evaluate and compare the antibacterial effect of BV from two different bee subspecies Apis mellifera yemenitica (A. m. yemenitica) (indigenous strain) and Apis mellifera carnica (A. m. carnica) (carniolan strain) against selected Gram-positive and Gram-negative bacteria. Experimentally, venoms were extracted using an electrical venom collector from honey bee colonies of the subspecies, A. m. yemenitica and A. m. carnica, in Hail, Saudi Arabia. Each venom was tested against selected medically important Gram-negative strains, Salmonella Typhimurium, Pseudomonas aeruginosa, and Escherichia coli, while Staphylococcus aureus was selected as Gram-positive test organism. The minimum inhibitory concentration (MIC) method was used to compare the effect of BV from the two subspecies on the growth of the selected bacterial strains. Results showed that BV from both subspecies could equally inhibit the growth of Salmonella Typhimurium, Pseudomonas aeruginosa, and Escherichia coli at an MIC of 10 mg/ml. However, S. aureus was inhibited by an MIC of 5 and 10 mg/ml of BV from A. m. carnica and A. m. yemenitica, respectively. This suggested that the BV of the carnica subspecie was more inhibitory to this Gram-positive pathogen than its counterpart produced by the yemenitica subspecies. The present study shows that bee venom has a promising antibacterial effect.
(© 2022. The Author(s) under exclusive licence to Sociedade Brasileira de Microbiologia.)
Databáze: MEDLINE
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