Studying the post-COVID-19 condition: research challenges, strategies, and importance of Core Outcome Set development.

Autor: Munblit D; Department of Paediatrics and Paediatric Infectious Diseases, Institute of Child's Health, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia. daniel.munblit08@imperial.ac.uk.; Inflammation, Repair and Development Section, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, UK. daniel.munblit08@imperial.ac.uk.; Research and Clinical Center for Neuropsychiatry, Moscow, Russia. daniel.munblit08@imperial.ac.uk., Nicholson TR; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Needham DM; Outcomes After Critical Illness and Surgery (OACIS) Research Group, Johns Hopkins University, Baltimore, MD, USA.; Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Seylanova N; Sechenov Biomedical Science and Technology Park, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia., Parr C; Faculty of Medicine, Imperial College London, London, UK., Chen J; Faculty of Medicine, Imperial College London, London, UK., Kokorina A; Pirogov Russian National Research Medical University, Moscow, Russia., Sigfrid L; ISARIC Global Support Centre, Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK., Buonsenso D; Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.; Dipartimento di Scienze Biotecnologiche di Base, Cliniche Intensivologiche e Perioperatorie, Università Cattolica del Sacro Cuore, Rome, Italy.; Global Health Research Institute, Istituto di Igiene, Università Cattolica del Sacro Cuore, Roma, Italy., Bhatnagar S; Maternal and Child Health Program, Translational Health Science and Technology Institute, Faridabad, Delhi, National Capital Region, India., Thiruvengadam R; Maternal and Child Health Program, Translational Health Science and Technology Institute, Faridabad, Delhi, National Capital Region, India., Parker AM; Outcomes After Critical Illness and Surgery (OACIS) Research Group, Johns Hopkins University, Baltimore, MD, USA.; Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Preller J; Clinical Management, WHO, WHE, Geneva, Switzerland., Avdeev S; Department of Pulmonology, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia., Klok FA; Department of Medicine - Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, the Netherlands., Tong A; Sydney School of Public Health, The University of Sydney, Sydney, Australia., Diaz JV; NCD Department, Rehabilitation Programme, WHO, Geneva, Switzerland., Groote W; NCD Department, Rehabilitation Programme, WHO, Geneva, Switzerland., Schiess N; WHO Brain Health Unit, Geneva, Switzerland., Akrami A; Sainsbury Wellcome Centre, UCL, London, UK.; Patient-Led Research Collaborative, Washington, DC, USA., Simpson F; Coventry University, Coventry, UK., Olliaro P; ISARIC Global Support Centre, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Apfelbacher C; Institute of Social Medicine and Health Systems Research, Faculty of Medicine, Otto von Guericke University Magdeburg, Magdeburg, Germany., Rosa RG; Critical Care Department, Hospital Moinhos de Vento, Porto Alegre, Brazil.; Brazilian Research in Intensive Care Network (BRICNet), São Paulo, Brazil., Chevinsky JR; COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, GA, USA.; Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA., Saydah S; COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, GA, USA.; Respiratory Viruses Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA., Schmitt J; Center for Evidence-Based Healthcare, Medical Faculty Carl Gustav Carus, TU Dresden, Dresden, Germany., Guekht A; Research and Clinical Center for Neuropsychiatry, Moscow, Russia.; Pirogov Russian National Research Medical University, Moscow, Russia., Gorst SL; Department of Health Data Science, University of Liverpool, Liverpool, UK., Genuneit J; Paediatric Epidemiology, Department of Pediatrics, Medical Faculty, Leipzig University, Leipzig, Germany., Reyes LF; Universidad de La Sabana, Chía, Colombia.; Clínica Universidad de La Sabana, Chía, Colombia., Asmanov A; The Research and Clinical Institute for Pediatrics named after Academician Yuri Veltischev of the Pirogov Russian National Research Medical University, Moscow, Russia., O'Hara ME; Long COVID Support, London, UK., Scott JT; MRC-University of Glasgow, Centre for Virus Research, Glasgow, UK., Michelen M; ISARIC Global Support Centre, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; School of Health Sciences, City, University of London, London, UK., Stavropoulou C; School of Health Sciences, City, University of London, London, UK., Warner JO; Paediatric Infectious Diseases, Imperial College Healthcare NHS Trust, London, UK., Herridge M; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada.; Department of Medicine, University Health Network, Toronto, ON, Canada., Williamson PR; MRC/NIHR Trials Methodology Research Partnership, Department of Health Data Science, University of Liverpool (a member of Liverpool Health Partners), Liverpool, UK.
Jazyk: angličtina
Zdroj: BMC medicine [BMC Med] 2022 Feb 04; Vol. 20 (1), pp. 50. Date of Electronic Publication: 2022 Feb 04.
DOI: 10.1186/s12916-021-02222-y
Abstrakt: Background: A substantial portion of people with COVID-19 subsequently experience lasting symptoms including fatigue, shortness of breath, and neurological complaints such as cognitive dysfunction many months after acute infection. Emerging evidence suggests that this condition, commonly referred to as long COVID but also known as post-acute sequelae of SARS-CoV-2 infection (PASC) or post-COVID-19 condition, could become a significant global health burden.
Main Text: While the number of studies investigating the post-COVID-19 condition is increasing, there is no agreement on how this new disease should be defined and diagnosed in clinical practice and what relevant outcomes to measure. There is an urgent need to optimise and standardise outcome measures for this important patient group both for clinical services and for research and to allow comparing and pooling of data.
Conclusions: A Core Outcome Set for post-COVID-19 condition should be developed in the shortest time frame possible, for improvement in data quality, harmonisation, and comparability between different geographical locations. We call for a global initiative, involving all relevant partners, including, but not limited to, healthcare professionals, researchers, methodologists, patients, and caregivers. We urge coordinated actions aiming to develop a Core Outcome Set (COS) for post-COVID-19 condition in both the adult and paediatric populations.
(© 2022. The Author(s).)
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje