Gene expression data of inflammatory mediators in apical periodontitis in 129 (wild type) and 5-lipoxygenase knockout mice.

Autor:	Taira TM; Department of Pediatric Clinics, School of Dentistry of Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Café s/n, 1° andar, sala M-28, CEP, São Paulo 14040-904, Brazil., Ribeiro VL; Department of Restorative Dentistry, School of Dentistry of Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, São Paulo, Brazil., Ribeiro YJS; Department of Pediatric Clinics, School of Dentistry of Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Café s/n, 1° andar, sala M-28, CEP, São Paulo 14040-904, Brazil., da Silva RAB; Department of Pediatric Clinics, School of Dentistry of Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Café s/n, 1° andar, sala M-28, CEP, São Paulo 14040-904, Brazil., da Silva LAB; Department of Pediatric Clinics, School of Dentistry of Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Café s/n, 1° andar, sala M-28, CEP, São Paulo 14040-904, Brazil., Politi MPL; Department of Pediatric Clinics, School of Dentistry of Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Café s/n, 1° andar, sala M-28, CEP, São Paulo 14040-904, Brazil., Faccioli LH; Departamento de Análises Clínicas, Toxicológicas e Bromatológicas da Faculdade de Ciências Farmacêuticas de Ribeirão Preto da Universidade de São Paulo, Ribeirão Preto, São Paulo, Brazil., Paula-Silva FWG; Department of Pediatric Clinics, School of Dentistry of Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Café s/n, 1° andar, sala M-28, CEP, São Paulo 14040-904, Brazil.
Jazyk:	angličtina
Zdroj:	Data in brief [Data Brief] 2022 Jan 10; Vol. 40, pp. 107787. Date of Electronic Publication: 2022 Jan 10 (Print Publication: 2022).
DOI:	10.1016/j.dib.2021.107787
Abstrakt:	Apical periodontitis is an immune inflammatory response around periapical tissues as a result of pathogens invasion into the root canal. The host immunoinflammatory response could determine the progression of this disease, which involves the recruitment of immune cells, and the release of several cytokines in the lesion site. The 5-lipoxygenase pathway has been activated in some osteolytic diseases due to its capacity to interfere in the proliferation and differentiation of bone cells, including the osteoclasts. As mean to understand the inflammatory genes regulation in the apical periodontitis progression, we evaluated the network of 66 genes related to cytokines, chemokines and other inflammatory mediators and receptors in the wild-type (WT) and 5-lipoxygenase enzyme genetically deficient mice (KO). This article presents data not published but related to the research article "Effects of 5-lipoxygenase gene disruption on inflammation, osteoclastogenesis and bone resorption in polymicrobial apical periodontitis" . Competing Interests: The authors declare no conflict of interest for this article. (© 2022 The Author(s). Published by Elsevier Inc.)
Databáze:	MEDLINE
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