A narrative review on the effects of a ketogenic diet on patients with Alzheimer's disease.
| Autor: | Tabaie EA; Department of Neurobiology, Physiology & Behavior, University of California, Davis, Davis, USA., Reddy AJ; Department of Ophthalmology, California Northstate University College of Medicine, Elk Grove, USA., Brahmbhatt H; Psychiatry, Mercy General Hospital, Sacramento, USA. |
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| Jazyk: | angličtina |
| Zdroj: | AIMS public health [AIMS Public Health] 2021 Dec 22; Vol. 9 (1), pp. 185-193. Date of Electronic Publication: 2021 Dec 22 (Print Publication: 2022). |
| DOI: | 10.3934/publichealth.2022014 |
| Abstrakt: | Alzheimer's disease (AD) has been very difficult to prevent and cure using the medicine available today. However, there has been some hope with using a ketogenic diet (KD) to reduce the cognitive and quality of life decline experienced by patients with AD. In this review, the authors discuss the research done on the effect of a KD on AD to provide some potential avenues for future research and to determine a KD that can be best adopted by patients. The authors also go over the effects of KD's and low-carbohydrate diets (LCDs) on the cognitive function of healthy patients and on patients without AD to determine the similar and dissimilar effects of the diets. The authors found that the KD was able to improve the cognitive abilities and quality of life of patients ranging from mild to severe AD. Several types of memory were improved as a result of the diets. Further research needs to be conducted to determine the cause behind these improvements. However, the several studies that were done were mostly in agreement that once ketosis was reached, cognitive improvements were observed in patients ranging from mild to severe AD or mild to moderate cognitive impairment. Through the use of a KD, potential mechanisms can be found to reduce the cognitive decline of patients with AD, and potentially even prevent the damaging effects of cognitive decline from AD altogether. Competing Interests: Conflict of interest: The authors declare no conflict of interest in this paper. (© 2022 the Author(s), licensee AIMS Press.) |
| Databáze: | MEDLINE |
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