[A Case of SM Carcinoma of the Sigmoid Colon with Distant Metastasis in the Early Stage after Endoscopic MucosalResection].

Autor:	Takashima J; Dept. of Surgery, Teikyo University School of Medicine Mizonokuchi Hospital., Kobayashi H, Suzuki Y, Koizumi A, Akasaki T, Shigehara F, Tsukamoto M, Yamasaki K, Sugimoto H, Fujimoto D, Miura F, Taniguchi K, Matsutani N, Takahashi M
Jazyk:	japonština
Zdroj:	Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2021 Dec; Vol. 48 (13), pp. 1631-1633.
Abstrakt:	Introduction: We report a case of submucosal(SM)adenocarcinoma of the sigmoid colon which developed distant metastasis 3 months after endoscopic mucosal resection(EMR). Case: 54-year-old, male. Colonoscopy, which was performed due to positive fecal occult blood test, revealed 18 mm Isp sigmoid polyp. EMR was performed with en bloc resection. Pathological examination revealed adenocarcinoma(tub>por>sig), pT1b, Ly1c, V1a, pHM0, and pVM1. Therefore, laparoscopic sigmoidectomy(D2 dissection)was performed. Postoperative pathological examination revealed pT1b, pN2b(10/11), PN1b, pPM0, pDM0, pStage Ⅲb. Distant nodal involvement were found on computed tomography 3 months after EMR, although systemic chemotherapy(mFOLFOX6 plus panitumumab 18 courses and FOLFIRI plus bevacizumab 4 courses)was performed, the patient died of liver failure caused by liver metastasis 21 months after EMR. Conclusion: We present a case of T1 sigmoid adenocarcinoma which developed distant metastasis 3 months after EMR with literature review.
Databáze:	MEDLINE
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