Severe Acute Respiratory Syndrome Type 2-Causing Coronavirus: Variants and Preventive Strategies.
| Autor: | Aydogdu MO; Department of Mechanical Engineering, University College London (UCL), Torrington Place, London, WC1E 7JE, UK., Rohn JL; Department of Renal Medicine, Division of Medicine, University College London, Rowland Hill Street, London, NW3 2PF, UK., Jafari NV; Department of Renal Medicine, Division of Medicine, University College London, Rowland Hill Street, London, NW3 2PF, UK., Brako F; Medway School of Pharmacy, Universities at Medway, Chatham, ME4 4TB, UK., Homer-Vanniasinkam S; Department of Mechanical Engineering, University College London (UCL), Torrington Place, London, WC1E 7JE, UK., Edirisinghe M; Department of Mechanical Engineering, University College London (UCL), Torrington Place, London, WC1E 7JE, UK. |
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| Jazyk: | angličtina |
| Zdroj: | Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2022 Apr; Vol. 9 (11), pp. e2104495. Date of Electronic Publication: 2022 Jan 17. |
| DOI: | 10.1002/advs.202104495 |
| Abstrakt: | COVID-19 vaccines have constituted a substantial scientific leap in countering severe acute respiratory syndrome type 2-causing coronavirus (SARS-CoV-2), and worldwide implementation of vaccination programs has significantly contributed to the global pandemic effort by saving many lives. However, the continuous evolution of the SARS-CoV-2 viral genome has resulted in different variants with a diverse range of mutations, some with enhanced virulence compared with previous lineages. Such variants are still a great concern as they have the potential to reduce vaccine efficacy and increase the viral transmission rate. This review summarizes the significant variants of SARS-CoV-2 encountered to date (December 2021) and discusses a spectrum of possible preventive strategies, with an emphasis on physical and materials science. (© 2022 The Authors. Advanced Science published by Wiley-VCH GmbH.) |
| Databáze: | MEDLINE |
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