Autor: |
Perri MR; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, CS, Italy., Romano C; SIACSA Società Italiana degli Analisti del Comportamento in campo Sperimentale ed Applicativo, 87100 Cosenza, RC, Italy., Marrelli M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, CS, Italy., Zicarelli L; Naturextralab S.R.L., 87040 Mendicino, CS, Italy., Toma CC; Pharmacognosy Department, Faculty of Pharmacy, Vasile Goldis Western University of Arad, 87 L. Rebreanu Str., 310045 Arad, Romania., Basta D; University Sport Center, University of Calabria, 87036 Rende, CS, Italy., Conforti F; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, CS, Italy., Statti G; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, CS, Italy. |
Abstrakt: |
Inflammatory bowel disease (IBD) is a group of complex chronic inflammatory conditions affecting the gastrointestinal tract. It is linked to a number of genetic and environmental factors able to perturb the immune-microbiome axis. Diet is the most investigated variable both for its role in the etiology of IBD and for its beneficial potential in the treatment of the symptoms. Dietary products may influence intestinal inflammation through different mechanisms of action, such as the modulation of inflammatory mediators, the alteration of gene expression, changes in gut permeability, and modifications in enteric flora composition. A consisting number of studies deal with the link between nutrition and microbial community, and particular attention is paid to plant-based foods. The effects of the dietary intake of different fruits have been investigated so far. This review aims to present the most recent studies concerning the beneficial potential of fruit consumption on human gut microbiota. Investigated plant species are described, and obtained results are presented and discussed in order to provide an overview of both in vitro and in vivo effects of fruits, their juices, and freeze-dried powders. |