Enteric glia bring fresh WNT to the intestinal stem cell niche.
| Autor: | Progatzky F; Development and Homeostasis of the Nervous System Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK., Pachnis V; Development and Homeostasis of the Nervous System Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK. Electronic address: vassilis.pachnis@crick.ac.uk. |
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| Jazyk: | angličtina |
| Zdroj: | Cell stem cell [Cell Stem Cell] 2022 Jan 06; Vol. 29 (1), pp. 3-4. |
| DOI: | 10.1016/j.stem.2021.12.003 |
| Abstrakt: | Intestinal stem cells continuously self-renew and differentiate into a variety of specialized epithelial cells that maintain gut health. New research in this issue of Cell Stem Cell (Baghdadi et al., 2022) shows that enteric glial cells regulate the intestinal stem cell niche during regeneration and disease through the production of WNT ligands. (Copyright © 2021 Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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