COVID-19: vaccination vs. hospitalization.

Autor: Uzun O; Department of Pulmonary Medicine, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey. oguzuzun67@yahoo.com.tr.; Ondokuz Mayıs Üniversitesi Göğüs Hst, 55139, Samsun, Turkey. oguzuzun67@yahoo.com.tr., Akpolat T; Department of Internal Medicine and Nephrology, Faculty of Medicine, Istinye University, Istanbul, Turkey., Varol A; Kepez State Hospital, Antalya, Turkey., Turan S; Department of Intensive Care Unit, Ankara City Hospital, Ankara, Turkey., Bektas SG; Department of Intensive Care Unit, Ankara City Hospital, Ankara, Turkey., Cetinkaya PD; Adana City Hospital, Adana, Turkey., Dursun M; Siirt Training and Research Hospital, Siirt, Turkey., Bakan N; Şehit Prof Dr İlhan Varank Training and Research Hospital, İstanbul, Turkey., Ketencioglu BB; Department of Pulmonary Disease, School of Medicine, Erciyes University, Kayseri, Turkey., Bayrak M; Kepez State Hospital, Antalya, Turkey., Baris SA; Department of Pulmonary Disease, School of Medicine, Kocaeli University, Kocaeli, Turkey., Guner R; Department of Infectious Diseases and Clinical Microbiology, Ankara City Hospital, Yildirim Beyazit University, Ankara, Turkey., Gunal O; Department of Infectious Diseases and Clinical Microbiology, Samsun Training and Research Hospital, University of Medical Science, Samsun, Turkey., Nural S; Department of Pulmonary Medicine, Training and Research Hospital, Hatay, İstanbul, Turkey., Deniz PP; City Hospital, Adana, Turkey., Toprak OB; Department of Pulmonary Medicine, Faculty of Medicine, Cukuroca University, Adana, Turkey., Ozkan G; Maslak Acibadem Hospital, Operating Room Services Department and Private Acıbadem Maslak Hospital, Vocational School, Nişantaşı University, İstanbul, Turkey., Gumus A; Kepez State Hospital, Antalya, Turkey., Kerget F; Department of Infection Diseases and Clinical Microbiology, Faculty of Medicine, Erzurum Regional Education and Research Hospital, Health Sciences University, Erzurum, Turkey., Ercelik M; Dinar State Hospital, Afyon, Turkey., Ataoglu O; Duzce Ataturk State Hospital, Duzce, Turkey., Yuksel A; Department of Pulmonary Medicine, Faculty of Medicine, Ufuk University, Ankara, Turkey., Ates G; Genesis Private Hospital, Diyarbakır, Turkey., Kutsoylu OE; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey., Kose N; Bilecik State Hospital, Bilecik, Turkey., Kizilirmak D; Department of Pulmonary Medicine, Faculty of Medicine, Celal Bayar University, Manisa, Turkey., Keskin S; Siirt Training and Research Hospital, Siirt, Turkey., Gultekin O; Oltu State Hospital, Erzurum, Turkey., Coskun N; Şehit Prof Dr İlhan Varank Training and Research Hospital, İstanbul, Turkey., Yilmaz ES; Department of Pulmonary Medicine, Medical Faculty, Training and Research Hospital, Ordu University, Ordu, Turkey., Uslu S; Department of Pulmonary Medicine, Medical Faculty, Training and Research Hospital, Ordu University, Ordu, Turkey., Basyigit İ; Department of Pulmonary Disease, School of Medicine, Kocaeli University, Kocaeli, Turkey., Ergan B; Division of Intensive Care, Department of Pulmonary and Critical Care, Faculty of Medicine, Dokuz Eylül University, Izmir, Turkey., Deveci F; Department of Pulmonary Medicine, Faculty of Medicine, Firat University, Elazıg, Turkey., Yakar MN; Division of Intensive Care, Department of Anaesthesiology and Reanimation, Faculty of Medicine, Dokuz Eylül University, Izmir, Turkey., Zuhur C; Private Gelisim Hospital, İskenderun, Turkey., Sagcan G; Private Altunizade Maslak Hospital, İstanbul, Turkey., Yuce ZT; Department of Infectious Diseases and Clinical Microbiology, Erciyes University, Kayseri, Turkey., Kuluozturk M; Department of Pulmonary Medicine, Faculty of Medicine, Firat University, Elazıg, Turkey., Sezgin ME; Siirt Training and Research Hospital, Siirt, Turkey., Sezgin ENA; Siirt Training and Research Hospital, Siirt, Turkey., Havlucu Y; Department of Pulmonary Medicine, Faculty of Medicine, Celal Bayar University, Manisa, Turkey., Cuhadaroglu C; Private Altunizade Maslak Hospital, İstanbul, Turkey., Kilinc O; Department of Pulmonary Medicine, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey., Boyaci H; Department of Pulmonary Disease, School of Medicine, Kocaeli University, Kocaeli, Turkey., Altunay H; Siirt Training and Research Hospital, Siirt, Turkey., Akti M; Siirt Training and Research Hospital, Siirt, Turkey., Dursun ZB; Department of Infectious Diseases and Clinical Microbiology, Kayseri City Hospital, Health Science University, Kayseri, Turkey., Kalem AK; Department of Infectious Diseases and Clinical Microbiology, Ankara City Hospital, Yildirim Beyazit University, Ankara, Turkey., Isik SA; Sultan Abdülhamid Han Training and Research Hospital, İstanbul, Turkey., Akyildiz L; Private Memorial Hospital, Diyarbakır, Turkey., Aykac N; Academic Hospital, İstanbul, Turkey., Almaz MS; Private Memorial Hospital, Diyarbakır, Turkey., Kokturk N; Department of Pulmonary Medicine, Faculty of Medicine, Gazi University, Ankara, Turkey., Itil O; Department of Pulmonary Medicine, Faculty of Medicine, Dokuz Eylul University, İzmir, Turkey.
Jazyk: angličtina
Zdroj: Infection [Infection] 2022 Jun; Vol. 50 (3), pp. 747-752. Date of Electronic Publication: 2022 Jan 04.
DOI: 10.1007/s15010-021-01751-1
Abstrakt: Objective: Vaccination is the most efficient way to control the coronavirus disease 2019 (COVID-19) pandemic, but vaccination rates remain below the target level in most countries. This multicenter study aimed to evaluate the vaccination status of hospitalized patients and compare two different booster vaccine protocols.
Setting: Inoculation in Turkey began in mid-January 2021. Sinovac was the only available vaccine until April 2021, when BioNTech was added. At the beginning of July 2021, the government offered a third booster dose to healthcare workers and people aged > 50 years who had received the two doses of Sinovac. Of the participants who received a booster, most chose BioNTech as the third dose.
Methods: We collected data from 25 hospitals in 16 cities. Patients hospitalized between August 1 and 10, 2021, were included and categorized into eight groups according to their vaccination status.
Results: We identified 1401 patients, of which 529 (37.7%) were admitted to intensive care units. Nearly half (47.8%) of the patients were not vaccinated, and those with two doses of Sinovac formed the second largest group (32.9%). Hospitalizations were lower in the group which received 2 doses of Sinovac and a booster dose of BioNTech than in the group which received 3 doses of Sinovac.
Conclusion: Effective vaccinations decreased COVID-19-related hospitalizations. The efficacy after two doses of Sinovac may decrease over time; however, it may be enhanced by adding a booster dose. Moreover, unvaccinated patients may be persuaded to undergo vaccination.
(© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany.)
Databáze: MEDLINE
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