Chorioamnionitis has no impact on immunohistochemical expression of IL-6 in placental membranes of the late preterm delivery regardless of the membrane status.

Autor:	Benzon Z; Department of Gynecology and Obstetrics, University Hospital and School of Medicine, University of Split, Split, Croatia., Kuzmić Prusac I; Institute for Pathology, University Hospital and School of Medicine, Split, Croatia., Zekić Tomaš S; Institute for Pathology, University Hospital and School of Medicine, Split, Croatia., Vulić M; Department of Gynecology and Obstetrics, University Hospital and School of Medicine, University of Split, Split, Croatia., Vulić L; Department of Gynecology and Obstetrics, University Hospital Center 'Sisters of Mercy', Zagreb, Croatia., Benzon S; Department of Gynecology and Obstetrics, University Hospital and School of Medicine, University of Split, Split, Croatia., Stefanovic V; Department of Obstetrics and Gynecology, Fetomaternal Medical Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Jazyk:	angličtina
Zdroj:	Journal of perinatal medicine [J Perinat Med] 2021 Dec 13; Vol. 50 (4), pp. 386-390. Date of Electronic Publication: 2021 Dec 13 (Print Publication: 2022).
DOI:	10.1515/jpm-2021-0542
Abstrakt:	Objectives: To compare the immunohistochemical expression of IL-6 in placental membranes of late preterm delivery in women with histologically proven chorioamnionitis with and without preterm premature rupture of membranes (PPROM). Methods: Fetal membranes were collected from 60 women who had late preterm delivery with histologic chorioamnionitis with and without PPROM (30 in each group). Immunohistochemistry for IL-6 was performed on formalin fixed and paraffin-embedded sections. The two groups were matched for age, body mass index and parity. SPSS Version 17.0 was used for statistical analysis. Results: There was no difference in immunohistochemical expression of IL-6 in placental membranes of women with histologic chorioamnionitis regardless of the membrane status. Conclusions: Chorioamnionitis has no impact on immunohistochemical expression of IL-6 in placental membranes of women with late preterm delivery despite the clinical presentation. (© 2021 Walter de Gruyter GmbH, Berlin/Boston.)
Databáze:	MEDLINE
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