Derivation of iPS cell line (ICGi032-A) from a patient affected with fragile X syndrome.

Autor:	Gridina MM; Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia., Shitik EM; State Research Center of Virology and Biotechnology 'Vector', Federal Service for Surveillance on Consumer Rights Protection and Human Well-being (FBRI SRC VB 'Vector', Rospotrebnadzor), Koltsovo, Novosibirsk Region, Russia., Lemskaya NA; Institute of Molecular and Cellular Biology, SB RAS, Novosibirsk, Russia., Minina JM; Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia., Grishchenko IV; State Research Center of Virology and Biotechnology 'Vector', Federal Service for Surveillance on Consumer Rights Protection and Human Well-being (FBRI SRC VB 'Vector', Rospotrebnadzor), Koltsovo, Novosibirsk Region, Russia., Dolskiy AA; State Research Center of Virology and Biotechnology 'Vector', Federal Service for Surveillance on Consumer Rights Protection and Human Well-being (FBRI SRC VB 'Vector', Rospotrebnadzor), Koltsovo, Novosibirsk Region, Russia., Shorina AR; SBIH Novosibirsk Municipal Clinical Hospital №1, Novosibirsk, Russia., Maksimova YV; SBIH Novosibirsk Municipal Clinical Hospital №1, Novosibirsk, Russia; Novosibirsk State Medical University, Novosibirsk, Russia., Yudkin DV; State Research Center of Virology and Biotechnology 'Vector', Federal Service for Surveillance on Consumer Rights Protection and Human Well-being (FBRI SRC VB 'Vector', Rospotrebnadzor), Koltsovo, Novosibirsk Region, Russia.
Jazyk:	angličtina
Zdroj:	Stem cell research [Stem Cell Res] 2021 Dec; Vol. 57, pp. 102615. Date of Electronic Publication: 2021 Nov 29.
DOI:	10.1016/j.scr.2021.102615
Abstrakt:	Trinucleotide repeat expansion diseases such as fragile X syndrome are of great interest to study since the mechanism of its development is still unknown. IPS cell lines are some of the most convenient models for studying. The ICGi032-A iPS cell line was obtained from the peripheral blood mononuclear cells of the patient affected with fragile X syndrome. ICGi032-A iPS cell line have a normal karyotype, expression of pluripotency markers and can differentiate in vitro into the cells of three germ layers. (Copyright © 2021 The Authors. Published by Elsevier B.V. All rights reserved.)
Databáze:	MEDLINE
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