Cutaneous metastasis of occult breast cancer: a case report.

Autor: da Costa REAR; State University of Piauí, Teresina, PI, Brazil., Dos Reis CA; Oncocenter, Teresina, PI, Brazil., Moura RD; Federal University of Piauí, Teresina, PI, Brazil., Araújo ALN; Oncocenter, Teresina, PI, Brazil., de Oliveira FTR; State University of Piauí, Teresina, PI, Brazil., Vieira SC; Oncocenter, Teresina, PI, Brazil.
Jazyk: angličtina
Zdroj: The Pan African medical journal [Pan Afr Med J] 2021 Sep 08; Vol. 40, pp. 23. Date of Electronic Publication: 2021 Sep 08 (Print Publication: 2021).
DOI: 10.11604/pamj.2021.40.23.31009
Abstrakt: Occult breast cancer (OBC) is characterized by metastatic presentation of undetectable breast tumor on imaging exams. OBC is a rare disease (accounting for 0.3% to 1.0% of all breast cancers) that represents a major diagnostic challenge. The aim of this study was to report a case of OBC with primary presentation of multiple cutaneous metastases with subsequent emergence of bone metastasis. A 70-year female patient had multiple cutaneous metastatic lesions in the left cervical region, left breast, left axillary region, left subscapular region, in three chirodactylus of the right hand and three chirodactylus of the left hand. Imaging tests (mammogram, ultrasonography and magnetic resonance imaging of the breast) did not show alterations. Biopsy, histology sections and immunohistochemistry of the left cervical cutaneous lesion were compatible with OBC. After two years of anastrozole treatment (1mg/day), there was regression of all cutaneous lesions and stabilization of bone metastasis. OBC has a better prognosis. It may exhibit spontaneous regression or respond to less aggressive treatment strategies, as described in this case.
Competing Interests: The authors declare no competing interests.
(Copyright: Rafael Everton Assunção Ribeiro da Costa et al.)
Databáze: MEDLINE