A State-of-the-Art Scoping Review on SARS-CoV-2 in Sewage Focusing on the Potential of Wastewater Surveillance for the Monitoring of the COVID-19 Pandemic.

Autor: Bonanno Ferraro G; Department of Environment and Health, Istituto Superiore di Sanità, Rome, Italy., Veneri C, Mancini P; Department of Environment and Health, Istituto Superiore di Sanità, Rome, Italy., Iaconelli M; Department of Environment and Health, Istituto Superiore di Sanità, Rome, Italy., Suffredini E; Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità, Rome, Italy., Bonadonna L; Department of Environment and Health, Istituto Superiore di Sanità, Rome, Italy., Lucentini L; Department of Environment and Health, Istituto Superiore di Sanità, Rome, Italy., Bowo-Ngandji A; Department of Microbiology, The University of Yaounde I, Yaounde, Cameroon., Kengne-Nde C; Research Monitoring and Planning Unit, National Aids Control Committee, Douala, Cameroon., Mbaga DS; Department of Microbiology, The University of Yaounde I, Yaounde, Cameroon., Mahamat G; Department of Microbiology, The University of Yaounde I, Yaounde, Cameroon., Tazokong HR; Department of Microbiology, The University of Yaounde I, Yaounde, Cameroon., Ebogo-Belobo JT; Medical Research Centre, Institute of Medical Research and Medicinal Plants Studies, Yaounde, Cameroon., Njouom R; Virology Department, Centre Pasteur of Cameroon, Yaounde, Cameroon., Kenmoe S; Virology Department, Centre Pasteur of Cameroon, Yaounde, Cameroon., La Rosa G; Department of Environment and Health, Istituto Superiore di Sanità, Rome, Italy. giuseppina.larosa@iss.it.
Jazyk: angličtina
Zdroj: Food and environmental virology [Food Environ Virol] 2022 Dec; Vol. 14 (4), pp. 315-354. Date of Electronic Publication: 2021 Nov 02.
DOI: 10.1007/s12560-021-09498-6
Abstrakt: The outbreak of coronavirus infectious disease-2019 (COVID-19), caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has rapidly spread throughout the world. Several studies have shown that detecting SARS-CoV-2 in untreated wastewater can be a useful tool to identify new outbreaks, establish outbreak trends, and assess the prevalence of infections. On 06 May 2021, over a year into the pandemic, we conducted a scoping review aiming to summarize research data on SARS-CoV-2 in sewage. Papers dealing with raw sewage collected at wastewater treatment plants, sewer networks, septic tanks, and sludge treatment facilities were included in this review. We also reviewed studies on sewage collected in community settings such as private or municipal hospitals, healthcare facilities, nursing homes, dormitories, campuses, airports, aircraft, and cruise ships. The literature search was conducted using the electronic databases PubMed, EMBASE, and Web Science Core Collection. This comprehensive research yielded 1090 results, 66 of which met the inclusion criteria and are discussed in this review. Studies from 26 countries worldwide have investigated the occurrence of SARS-CoV-2 in sewage of different origin. The percentage of positive samples in sewage ranged from 11.6 to 100%, with viral concentrations ranging from ˂LOD to 4.6 × 10 8 genome copies/L. This review outlines the evidence currently available on wastewater surveillance: (i) as an early warning system capable of predicting COVID-19 outbreaks days or weeks before clinical cases; (ii) as a tool capable of establishing trends in current outbreaks; (iii) estimating the prevalence of infections; and (iv) studying SARS-CoV-2 genetic diversity. In conclusion, as a cost-effective, rapid, and reliable source of information on the spread of SARS-CoV-2 and its variants in the population, wastewater surveillance can enhance genomic and epidemiological surveillance with independent and complementary data to inform public health decision-making during the ongoing pandemic.
(© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
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