Electrocardiographic Abnormalities in Patients With Spinal Cord Injury With Deranged Lipid Profile.

Autor:	Syed MUS; Internal Medicine, Dow University of Health Sciences, Karachi, PAK., Khan Z; Accident and Emergency, Kingston Hospital, London, GBR., Zulfiqar A; Internal Medicine, Dow Medical College, Karachi, PAK., Basham MA; Internal Medicine, Dow University of Health Sciences, Karachi, PAK., Abdul Haseeb H; Internal Medicine, Mayo Hospital, Lahore, PAK., Azizullah S; Internal Medicine, Dow University of Health Sciences, Karachi, PAK., Ismail H; Medicine and Surgery, Royal College of Surgeons in Ireland, Dublin, IRL., Elbahnasawy M; Internal Medicine, Alexandria Faculty of Medicine, Alexandria University, Alexandria, EGY., Nadeem Z; Internal Medicine, Dow University of Health Sciences, Karachi, PAK., Karimi S; Orthopedic Surgery, Dow University of Health Sciences, Karachi, PAK.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2021 Sep 24; Vol. 13 (9), pp. e18246. Date of Electronic Publication: 2021 Sep 24 (Print Publication: 2021).
DOI:	10.7759/cureus.18246
Abstrakt:	Introduction Spinal cord injury (SCI) can lead to severe disability and neurogenic shock, arrhythmias, autonomic dysfunction, pressure ulcers, etc., of the autonomic nervous system. Therefore, in these patients, cardiovascular problems should be investigated frequently. This study was conducted to evaluate the electrocardiographic (ECG) abnormalities in patients with spinal cord injury having inappropriate lipid profiles and their relationship with each other. Materials and methods This cross-sectional study was held in the Internal Medicine Department of Mayo Hospital, Lahore, for a one-year duration from May 2020 to May 2021. It included 58 patients with spinal cord injury, 35 of whom had paraplegia, and 23 had tetraplegia. Fasting blood samples were taken for lipid profile analysis. Twelve-lead ECGs three times a day for one month were taken and analyzed in the context of previously available ECGs. Results Out of 58, the lipid profiles were found abnormal in 47 patients, 18 of whom had a normal ECG. The lipid profile was normal in 12, of which only one patient had ECG abnormalities. Cholesterol levels were found normal in 39 patients and deranged in 19 patients; low-density lipoproteins in nine patients, triglycerides in 18 patients, and high-density lipoprotein values in one patient were abnormal. Conclusions Sinus bradycardia was the most common ECG abnormality found in SCI patients with deranged lipid profiles. Further studies are needed in the future to validate the findings of this study. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2021, Syed et al.)
Databáze:	MEDLINE
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