Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment.

Autor: Belda W Jr; Dermatology Department, University of São Paulo, Medical School, Clinics Hospital, São Paulo, Brazil.; Laboratory of Pathology of Infectious Diseases, Medical School, University of São Paulo, São Paulo, Brazil., Domingues Passero LF; São Paulo State University (UNESP), Institute of Biosciences, São Vicente, Presidente Prudente, Brazil.; São Paulo State University (UNESP), Institute for Advanced Studies of Ocean, São Vicente, Presidente Prudente, Brazil., Stradioto Casolato AT; Dermatology Department, University of São Paulo, Medical School, Clinics Hospital, São Paulo, Brazil.
Jazyk: angličtina
Zdroj: Case reports in dermatological medicine [Case Rep Dermatol Med] 2021 Oct 06; Vol. 2021, pp. 9453701. Date of Electronic Publication: 2021 Oct 06 (Print Publication: 2021).
DOI: 10.1155/2021/9453701
Abstrakt: Sporotrichosis is a fungal infection endemic in Latin America and has been attributed to the thermodimorphic fungus of the genus Sporothrix . Transmission to humans occurs during a traumatic injury with soil or organic material; additionally, lesions caused by infected cats play an important role in the epidemiology of the disease. The classic treatment of sporotrichosis is performed with itraconazole or potassium iodide; second-line medications, such as amphotericin B and terbinafine, can alternatively be used in cases of first-line drug failure. In the present study, a patient with lymphocutaneous sporotrichosis in the right upper limb exhibited intolerance to itraconazole and potassium iodide, additionally during the period of use; these drugs did not control skin lesions. In this patient, amphotericin B deoxycholate and its liposomal version were used in this patient; and complete recovery of the lesions was observed.
Competing Interests: The authors declare that there are no conflicts of interest regarding the publication of this article.
(Copyright © 2021 Walter Belda Jr. et al.)
Databáze: MEDLINE
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