Effects of Curcumin Supplementation on Inflammatory Markers, Muscle Damage, and Sports Performance during Acute Physical Exercise in Sedentary Individuals.

Autor: Dias KA; Department of Nutrition and Health, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil., da Conceição AR; Department of Nutrition and Health, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil., Oliveira LA; Department of Nutrition and Health, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil., Pereira SMS; Department of Nutrition and Health, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil., Paes SDS; Department of Nutrition and Health, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil., Monte LF; Department of Nutrition and Health, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil., Sarandy MM; Department of General Biology, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil., Novaes RD; Department of Structural Biology, Universidade Federal de Alfenas, Alfenas, Minas Gerais, Brazil., Gonçalves RV; Department of General Biology, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil., Della Lucia CM; Department of Nutrition and Health, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil.
Jazyk: angličtina
Zdroj: Oxidative medicine and cellular longevity [Oxid Med Cell Longev] 2021 Oct 07; Vol. 2021, pp. 9264639. Date of Electronic Publication: 2021 Oct 07 (Print Publication: 2021).
DOI: 10.1155/2021/9264639
Abstrakt: Exhaustive and acute unusual physical exercise leads to muscle damage. Curcumin has been widely studied due to the variety of its biological activities, attributed to its antioxidant and anti-inflammatory properties. Furthermore, it has shown positive effects on physical exercise practitioners. However, there is no literature consensus on the beneficial effects of curcumin in acute physical activities performed by sedentary individuals. Therefore, we systematically reviewed evidence from clinical trials on the main effects of curcumin supplementation on inflammatory markers, sports performance, and muscle damage during acute physical exercises in these individuals. We searched PubMed/MEDLINE, Scopus, Web of Science, and Embase databases, and only original studies were analyzed according to the PRISMA guidelines. The included studies were limited to supplementation of curcumin during acute exercise. A total of 5 studies were selected. Methodological quality assessments were examined using the SYRCLE's risk-of-bias tool. Most studies have shown positive effects of curcumin supplementation in sedentary individuals undergoing acute physical exercise. Overall, participants supplemented with curcumin showed less muscle damage, reduced inflammation, and better muscle performance. The studies showed heterogeneous data and exhibited methodological limitations; therefore, further research is necessary to ensure curcumin supplementation benefits during acute and high-intensity physical exercises. Additionally, mechanistic and highly controlled studies are required to improve the quality of the evidence and to elucidate other possible mechanisms. This study is registered with Prospero number CRD42021262718.
Competing Interests: The authors declare that they have no conflict of interest.
(Copyright © 2021 Kelly Aparecida Dias et al.)
Databáze: MEDLINE
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