Multiscale Microtubule Dynamics in Active Nematics.
| Autor: | Lemma LM; Department of Physics, Brandeis University, Waltham, Massachusetts 02453, USA.; Department of Physics, University of California at Santa Barbara, Santa Barbara, California 93106, USA., Norton MM; Department of Physics, Brandeis University, Waltham, Massachusetts 02453, USA., Tayar AM; Department of Physics, University of California at Santa Barbara, Santa Barbara, California 93106, USA., DeCamp SJ; Department of Physics, Brandeis University, Waltham, Massachusetts 02453, USA., Aghvami SA; Department of Physics, Brandeis University, Waltham, Massachusetts 02453, USA., Fraden S; Department of Physics, Brandeis University, Waltham, Massachusetts 02453, USA., Hagan MF; Department of Physics, Brandeis University, Waltham, Massachusetts 02453, USA., Dogic Z; Department of Physics, Brandeis University, Waltham, Massachusetts 02453, USA.; Department of Physics, University of California at Santa Barbara, Santa Barbara, California 93106, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Physical review letters [Phys Rev Lett] 2021 Oct 01; Vol. 127 (14), pp. 148001. |
| DOI: | 10.1103/PhysRevLett.127.148001 |
| Abstrakt: | In microtubule-based active nematics, motor-driven extensile motion of microtubule bundles powers chaotic large-scale dynamics. We quantify the interfilament sliding motion both in isolated bundles and in a dense active nematic. The extension speed of an isolated microtubule pair is comparable to the molecular motor stepping speed. In contrast, the net extension in dense 2D active nematics is significantly slower; the interfilament sliding speeds are widely distributed about the average and the filaments exhibit both contractile and extensile relative motion. These measurements highlight the challenge of connecting the extension rate of isolated bundles to the multimotor and multifilament interactions present in a dense 2D active nematic. They also provide quantitative data that is essential for building multiscale models. |
| Databáze: | MEDLINE |
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