Clinical and epidemiological characteristics of patients hospitalized for SARS-CoV-2 infection in two hospitals in Córdoba.

Autor:	Saad EJ; Hospital Privado universitario de Córdoba. emanuelsaad@hotmail.com., Correa Barovero MA; Hospital Privado Universitario de Córdoba. antocorrea77@gmail.com., Marucco FA; Hospital Privado Universitario de Córdoba, Instituto universitario de Ciencias Biomédicas de Córdoba. fedemarucco79@gmail.com., Rodríguez Bonazzi ST; Hospital Privado Universitario de Córdoba. silvitrb@gmail.com., Tarditi Barra A; Hospital Privado Universitario de Córdoba. ayetarditi@gmail.com., Zlotogora M; Hospital Privado Universitario de Córdoba. melizloto@gmail.com., Villada SM; Hospital Privado Universitario de Córdoba. sofivillada14@gmail.com., Douthat Y Barrionuevo A; Hospital Privado Universitario de Córdoba. douthataug@gmail.com., Heredia MC; Hospital Privado Universitario de Córdoba, Instituto universitario de Ciencias Biomédicas de Córdoba. celesteheredia62@gmail.com., Caeiro JP; Hospital Privado Universitario de Córdoba, Instituto universitario de Ciencias Biomédicas de Córdoba. jpcaeiro3@gmail.com., Fernández P; Hospital Privado Universitario de Córdoba, Instituto Universitario de Ciencias Biomédicas de Córdoba. pehuenfernandez@hotmail.com., Albertini RA; Hospital Privado Universitario de Córdoba, Instituto Universitario de Ciencias Biomédicas de Córdoba. ricartualbertini@hotmail.com.
Jazyk:	Spanish; Castilian
Zdroj:	Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) [Rev Fac Cien Med Univ Nac Cordoba] 2021 Sep 23; Vol. 78 (3), pp. 303-312. Date of Electronic Publication: 2021 Sep 23.
DOI:	10.31053/1853.0605.v78.n3.32518
Abstrakt:	Introduction: COVID-19 disease shows a marked heterogeneity in its clinical course, with descriptions of some factors associated with a worse prognosis. Knowledge of the disease behavior in the local scenario is relevant to allow a better approach. Methods: Retrospective study in two hospitals in the city of Córdoba, Argentina, with patients aged 18 years or more, hospitalized for active SARS-CoV-2 infection, from March to October, 2020. Results: 448 patients were included, of which 95.75% corresponded to COVID-19 pneumonia. Most of the episodes occurred in men (63.6%), the median age was 63 years (IQR: 53-75), and the most frequent comorbidities were arterial hypertension (55.1%), obesity (31.7%) and diabetes mellitus (28.1%). 162 patients (36.2%) needed admission to the intensive care unit and 66 (14.7%) were placed on mechanical ventilation. 67 patients (15%) died within the first 30 days of follow-up. In the multivariate analysis, the only independent variable predictive of mortality at 30 days was age (adjusted Odds ratio [aOR] = 1.08, 95% CI = 1.04-1.11, p <0.001). The 4C-Score and CALL-Score prognostic scores showed good discrimination (Area under the curve [AUC] = 0.766, 95% CI = 0.72-0.80 and AUC = 0.785, 95% CI = 0.70-0.85 respectively) and the predicted percentages of mortality were quite close to what was observed in the present study. Conclusions: Most of the patients hospitalized with SARS-CoV-2 infection presented comorbidities and were admitted with pneumonia, associated with high mortality. The prognostic scores with the best performance to predict complications were the 4C-score and the CALL-score. (Universidad Nacional de Córdoba)
Databáze:	MEDLINE
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