Localization of the human haptoglobin genes distal to the fragile site at 16q22 using in situ hybridization.

Autor: Simmers RN, Stupans I, Sutherland GR
Jazyk: angličtina
Zdroj: Cytogenetics and cell genetics [Cytogenet Cell Genet] 1986; Vol. 41 (1), pp. 38-41.
DOI: 10.1159/000132193
Abstrakt: The distamycin A-sensitive fragile site fra(16)(q22) is a precisely localized chromosomal marker. When expressed at metaphase, it visibly separates the chromosome material on either side of the fragile site. Using a cDNA probe encoding both the alpha and beta haptoglobin chains, the haptoglobin loci were found by in situ hybridization to be distal to fra(16)(q22).
Databáze: MEDLINE