| Autor: |
Kelley EL; Portal Instruments, Cambridge, MA, USA., Smith RH; Portal Instruments, Cambridge, MA, USA., Corcoran G; Portal Instruments, Cambridge, MA, USA., Nygren S; Portal Instruments, Cambridge, MA, USA., Jacoski MV; Portal Instruments, Cambridge, MA, USA., Fernandes A; Portal Instruments, Cambridge, MA, USA. |
| Jazyk: |
angličtina |
| Zdroj: |
Drug delivery [Drug Deliv] 2021 Dec; Vol. 28 (1), pp. 1915-1922. |
| DOI: |
10.1080/10717544.2021.1976309 |
| Abstrakt: |
Needle-free injection is a desirable goal for many reasons, including reducing pain, anxiety, and eliminating safety risks associated with needle-stick injuries. However, development of a safe, reliable needle-free device optimized for at-home use has been met with many challenges. Portal Instruments Inc. has been developing needle-free medication delivery using a well-designed hand-held device, PRIME, that is safe, intuitive to use, and utilizes advanced electronic control of a focused, high velocity, pressurized liquid injection stream. The PRECISE II human study demonstrated that the PRIME needle-free injection system was safe, well tolerated, and strongly preferred by participants for self-injections over a standard needle and syringe. In addition, the study was able to be completed early for superiority following the success of the pre-defined interim analysis. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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