Whole-body hybrid positron emission tomography imaging yields clinically relevant information in the staging and restaging of sinonasal tumors.

Autor: Maurer A; Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Meerwein CM; Department of Otorhinolaryngology - Head & Neck Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Soyka MB; Department of Otorhinolaryngology - Head & Neck Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Grünig H; Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Skawran S; Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Mühlematter UJ; Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Messerli M; Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Mader CE; Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Husmann L; Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Rupp NJ; Department of Molecular Pathology, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Holzmann D; Department of Otorhinolaryngology - Head & Neck Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Huellner MW; Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Jazyk: angličtina
Zdroj: Head & neck [Head Neck] 2021 Nov; Vol. 43 (11), pp. 3572-3585. Date of Electronic Publication: 2021 Sep 13.
DOI: 10.1002/hed.26856
Abstrakt: Background: Whole-body hybrid positron emission tomography (PET) imaging is increasingly used for sinonasal tumors. However, only empirical data exist on the additional, clinically relevant information derived from these techniques.
Methods: This study included 96 regionalized magnetic resonance imaging (MRI) of the sinonasal tract/neck and separate hybrid FDG-PET/CT or FDG-PET/MRI in 74 patients. Additional radiological information (ARI) obtained from each hybrid examination was analyzed and its clinically relevance was determined. Clinically relevant information (CRI) was categorized with regard to primary tumor site, regional lymph node metastases, distant metastases, second primary tumors, and non-neoplastic findings.
Results: A total of 45/96 (46.9%) hybrid PET examinations revealed ARI. CRI was found in 32/96 (33.3%) examinations and concerned the primary tumor site (6.1%), regional lymph node metastases (4.1%), distant metastases (14.3%), second primary tumors (7.3%), and non-neoplastic findings (5.1%).
Conclusions: Hybrid PET imaging yields additional radiological information translating into clinically relevant information in a substantial proportion of patients with sinonasal tumors.
(© 2021 The Authors. Head & Neck published by Wiley Periodicals LLC.)
Databáze: MEDLINE
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