Tongue acceleration in humans evoked with intramuscular electrical stimulation of genioglossus.

Autor: Luu BL; Neuroscience Research Australia, Randwick, NSW, Australia., Walsh LD; Neuroscience Research Australia, Randwick, NSW, Australia; University of New South Wales, Sydney, NSW, Australia; Platypus Technical Consultants Pty Ltd, Canberra, Australia., Hübner PP; Neuroscience Research Australia, Randwick, NSW, Australia; University of New South Wales, Sydney, NSW, Australia., Eckert DJ; Neuroscience Research Australia, Randwick, NSW, Australia; University of New South Wales, Sydney, NSW, Australia; Adelaide Institute for Sleep Health, Flinders University, Bedford Park, SA, Australia., Bilston LE; Neuroscience Research Australia, Randwick, NSW, Australia; University of New South Wales, Sydney, NSW, Australia., Gandevia SC; Neuroscience Research Australia, Randwick, NSW, Australia; University of New South Wales, Sydney, NSW, Australia., Butler JE; Neuroscience Research Australia, Randwick, NSW, Australia; University of New South Wales, Sydney, NSW, Australia. Electronic address: j.butler@neura.edu.au.
Jazyk: angličtina
Zdroj: Respiratory physiology & neurobiology [Respir Physiol Neurobiol] 2022 Jan; Vol. 295, pp. 103786. Date of Electronic Publication: 2021 Sep 08.
DOI: 10.1016/j.resp.2021.103786
Abstrakt: Genioglossus was stimulated intramuscularly to determine the effect of regional activation of the muscle on tongue movement in eight healthy adults. Stimulation at motor threshold was delivered with a needle electrode inserted to different depths in the anterior and posterior regions of genioglossus. The current amplitude that induced muscle contraction was ∼80% higher for anterior than posterior sites. Evoked tongue movements were determined from stimulus-triggered averages (150 pulses) of the outputs from an accelerometer fixed to the posterosuperior surface of the tongue. The median amplitude [95% confidence intervals] for the resultant acceleration was 0.0 m/s 2 [0.0, 0.2] for anterior and 0.6 m/s 2 [0.1, 2.8] for posterior sites. There was a positive relationship between acceleration amplitude and stimulation depth in the posterior of genioglossus (p < 0.001), but acceleration amplitude did not vary with stimulation depth in the anterior region (p = 0.83). This heterogeneity in acceleration responses between muscle regions may contribute to differences in collapsibility of the upper airway.
(Copyright © 2021 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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