Impact of obesity on quality of life, psychological status, and disease activity in psoriatic arthritis: a multi‑center study.

Autor: Gok K; Rheumatology Clinic, Ankara City Hospital, Ankara, Turkey. kevserorhangok@gmail.com., Nas K; Division of Rheumatology and Immunology, Department of Physical Medicine and Rehabilitation, Sakarya University School of Medicine, Sakarya, Turkey., Tekeoglu I; Division of Rheumatology and Immunology, Department of Physical Medicine and Rehabilitation, Sakarya University School of Medicine, Sakarya, Turkey., Sunar I; Rheumatology Clinic, Aydın State Hospital, Aydın, Turkey., Keskin Y; Department of Physical Medicine and Rehabilitation, Bezmiâlem Vakif University, İstanbul, Turkey., Kilic E; Rheumatology Clinic, Kanuni Training and Research Hospital, Trabzon, Turkey., Sargin B; Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Adnan Menderes University School of Medicine, Aydın, Turkey., Acer Kasman S; Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Marmara University School of Medicine, İstanbul, Turkey., Alkan H; Department of Physical Medicine and Rehabilitation, Pamukkale University School of Medicine, Denizli, Turkey., Sahin N; Department of Physical Medicine and Rehabilitation, Balıkesir University School of Medicine, Balıkesir, Turkey., Cengiz G; Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Erciyes University School of Medicine, Kayseri, Turkey., Cuzdan N; Rheumatology Clinic, Balıkesir Atatürk City Hospital, Balıkesir, Turkey., Albayrak Gezer İ; Department of Physical Medicine and Rehabilitation, Selçuk University School of Medicine, Konya, Turkey., Keskin D; Department of Physical Medicine and Rehabilitation, Kırıkkale University School of Medicine, Kırıkkale, Turkey., Mulkoglu C; Department of Physical Medicine and Rehabilitation, Ankara Training and Research Hospital, Ankara, Turkey., Resorlu H; Department of Physical Medicine and Rehabilitation, Çanakkale Onsekiz Mart University School of Medicine, Çanakkale, Turkey., Bal A; Department of Physical Medicine and Rehabilitation, University of Health Sciences Ankara Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey., Duruoz MT; Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Marmara University School of Medicine, İstanbul, Turkey., Kucukakkas O; Department of Physical Medicine and Rehabilitation, Bezmiâlem Vakif University, İstanbul, Turkey., Yurdakul OV; Department of Physical Medicine and Rehabilitation, Bezmiâlem Vakif University, İstanbul, Turkey., Alkan Melikoglu M; Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Atatürk University School of Medicine, Erzurum, Turkey., Aydin Y; Department of Physical Medicine and Rehabilitation, Tekirdağ Kapaklı State Hospital, Tekirdağ, Turkey., Ayhan FF; Department of Physical Medicine and Rehabilitation, Atilim University Medical School, Ankara, Turkey., Bodur H; Department of Physical Medicine and Rehabilitation, Yıldırım Beyazıt University School of Medicine, Ankara, Turkey., Calis M; Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Erciyes University School of Medicine, Kayseri, Turkey., Capkin E; Department of Physical Medicine and Rehabilitation, Karadeniz Technical University School of Medicine, Trabzon, Turkey., Devrimsel G; Department of Physical Medicine and Rehabilitation, Recep Tayyip Erdoğan University School of Medicine, Rize, Turkey., Ecesoy H; Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Necmettin Erbakan University Meram School of Medicine, Konya, Turkey., Hizmetli S; Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Cumhuriyet University School of Medicine, Sivas, Turkey., Kamanli A; Division of Rheumatology and Immunology, Department of Physical Medicine and Rehabilitation, Sakarya University School of Medicine, Sakarya, Turkey., Kutluk O; Rheumatology Clinic, Antalya Training and Research Hospital, Antalya, Turkey., Sen N; Rheumatology Clinic, Kartal Dr. Lutfi Kirdar Training and Research Hospital, İstanbul, Turkey., Sendur OF; Department of Physical Medicine and Rehabilitation and Algology, Medicana International Hospital, İzmir, Turkey., Tolu S; Department of Physical Medicine and Rehabilitation, Medipol University School of Medicine, Istanbul, Turkey., Toprak M; Department of Physical Medicine and Rehabilitation, Yuzuncu Yıl University School of Medicine, Van, Turkey., Tuncer T; Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Akdeniz University School of Medicine, Antalya, Turkey.
Jazyk: angličtina
Zdroj: Rheumatology international [Rheumatol Int] 2022 Apr; Vol. 42 (4), pp. 659-668. Date of Electronic Publication: 2021 Aug 28.
DOI: 10.1007/s00296-021-04971-8
Abstrakt: This article aims to evaluate the possible effect of obesity on quality of life, psychological status, and other clinical variables in Psoriatic arthritis (PsA). PsA patients have been recruited by the Turkish League Against Rheumatism-Network from various centers in Turkey in this cross-sectional study. Patients with a body mass index (BMI) ≥ of 30 kg/m 2 were considered obese. Differences among patients with regard to obesity status were assessed with health-related quality of life measures (PsA Quality of Life Questionnaire [PsAQoL]), psychological status (Hospital Anxiety and Depression Scale [HADS]), and disease activity parameters (the Disease Activity index for PSoriatic Arthritis [DAPSA], Disease Activity Score 28-C-reactive protein [DAS28-CRP], Bath Ankylosing Spondylitis Disease Activity Index [BASDAI], Psoriasis Area and Severity Index [PASI]), physical functions (Ankylosing Spondylitis Functional Index [BASFI], Health Assessment Questionnaire [HAQ], and Health Assessment Questionnaire for the spondyloarthropathies [HAQ-S]). Pain was assessed using visual analog scale of pain (VAS-P), and fatigue was evaluated using visual analog scale of fatigue (VAS-F) and Functional Assessment of Chronic Illness Therapy (FACIT). A total of 1033 patients with PsA, 650 (62.9%) non-obese and 383 (37.1%) obese were included in the study. The PsAQoL, HADS-Anxiety, HADS-Depression, DAPSA, DAS28-CRP, BASDAI, BASFI, HAQ and HAQ-S scores of the obese group were higher than the non-obese group (p < 0.05). VAS-P and PASI scores were similar between group of patients with and without obesity. Obese patients had higher median scores of VAS-F and FACIT than non-obese patients (p < 0.05). Linear regression analysis showed that BMI affects the quality of life, depression, and disease activity. Consequently, obesity has significant associations with higher disease activity, lower QoL, risk of anxiety, depression, and fatigue. Therefore, obesity should also be taken into account in the management of PsA patients.
(© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
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