Assessment of C-Reactive Protein Level in Oral Submucous Fibrosis and Oral Squamous Cell Carcinoma Patient.

Autor: Sharma G; Department of Oral Pathology, Sarjug Dental College, Darbhanga, India., Kumar R; Department of Periodontics and Oral Implantology, Patna Dental College and Hospital, Bihar, India., Salam SA; Department of Periodontics and Oral Implantology, Patna Dental College and Hospital, Bihar, India., Bhasin P; Department of Conservative Dentistry and Endodontics, Shree Bankey Bihari Dental College, Ghaziabad, Uttar Pradesh, India., Tewari NK; Department of Dentistry, Nalanda Medical College and Hospital, Patna, Bihar, India., Yadav S; Department of Oral and Maxillofacial Surgery, I.T.S Dental College, Ghaziabad, Uttar Pradesh, India.
Jazyk: angličtina
Zdroj: Journal of pharmacy & bioallied sciences [J Pharm Bioallied Sci] 2021 Jun; Vol. 13 (Suppl 1), pp. S748-S750. Date of Electronic Publication: 2021 Jun 05.
DOI: 10.4103/jpbs.JPBS_607_20
Abstrakt: Background: Potentially malignant disorders are highly prevalent in India. In this study, we assessed C-reactive protein (CRP) levels in patients with oral submucous fibrosis (OSMF) and oral squamous cell carcinoma (OSCC).
Methodology: Sixty-four patients (OSMF and OSCC) were undertaken and were classified into 3 groups, OSMF patients (Group I, 34), OSCC (Group II, 30), and healthy controls (Group III, 26). Immunoturbidimetry method was used for the estimation of CRP levels.
Results: Maximum cases in Group I was seen in the age group 40-60 years (males-10, females-3), Group II in the age group 40-60 years (males-11, females-5) and Group III (males-5, females-6). The mean CRP level in Group I was 6.12 ± 4.5 mg/l, in Group II was 28.4 ± 21.5 mg/l, and in Group III was 3.15 ± 2.19 mg/l. The difference was significant ( P < 0.05).
Conclusion: Authors found that OSMF and oral cancer patients had increased CRP levels as compared to healthy subjects.
Competing Interests: There are no conflicts of interest.
(Copyright: © 2021 Journal of Pharmacy and Bioallied Sciences.)
Databáze: MEDLINE
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